Anti-EPN2 Antibody (CAB16106)
- SKU:
- CAB16106
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-EPN2 Antibody |
| 抗体コード: | CAB16106 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_683723.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | U-87MG, LO2, HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-300 of human EPN2 (NP_683723.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GINV REKS KQLV ALLK DEER LKAE RAQA LKTK ERMA QVAT GMGS NQIT FGRG SSQP NLST SHSE QEYG KAGG SPAS YHGS TSPR VSSE LEQA RPQT SGEE ELQL QLAL AMSR EVAE QEER LRRG DDLR LQMA LEES RRDT VKIP KKKE HGSL PQQT TLLD LMDA LPSS GPAA QKAE PWGP S |
| 遺伝子ID: | 22905 |
| Uniprot: | O95208 |
| セルラーロケーション: | Cytoplasm, Cytoplasmic vesicle, clathrin-coated vesicle |
| 計算された分子量: | 36kDa/57kDa/62kDa/68kDa |
| 観察された分子量: | 70kDa |
| 同義語: | EPN2, EHB21, epsin-2 |
| バックグラウンド: | This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | epsin 2: Plays a role in the formation of clathrin-coated invaginations and endocytosis. Belongs to the epsin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; nucleoplasm Molecular Function:lipid binding; protein binding Biological Process: embryonic organ development; endocytosis; in utero embryonic development; Notch signaling pathway; regulation of endocytosis |
| NCBI Summary: | This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95208 |
| NCBI GenInfo Identifier: | 218512093 |
| NCBI Gene ID: | 22905 |
| NCBI Accession: | O95208.3 |
| UniProt Secondary Accession: | O95208,O95207, Q52LD0, Q9H7Z2, Q9UPT7, A8MTV8, B3KRX8 E9PBC2, |
| UniProt Related Accession: | O95208 |
| Molecular Weight: | 36,729 Da |
| NCBI Full Name: | Epsin-2 |
| NCBI Synonym Full Names: | epsin 2 |
| NCBI Official Symbol: | EPN2 |
| NCBI Official Synonym Symbols: | EHB21 |
| NCBI Protein Information: | epsin-2 |
| UniProt Protein Name: | Epsin-2 |
| UniProt Synonym Protein Names: | EPS-15-interacting protein 2 |
| UniProt Gene Name: | EPN2 |
| UniProt Entry Name: | EPN2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using EPN2 antibody (CAB16106) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
 | Immunohistochemistry of paraffin-embedded Human colon carcinoma using EPN2 Rabbit pAb (CAB16106) at dilution of 1:100 (40x lens). |
View AllClose