Anti-EPN1 Antibody (CAB17695)
- SKU:
- CAB17695
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-EPN1 Antibody |
| 抗体コード: | CAB17695 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human EPN1 (NP_037465.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Mouse lung, Mouse liver, Mouse kidney, Rat testis, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human EPN1 (NP_037465.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LVAL LRDE DRLR EERA HALK TKEK LAQT ATAS SAAV GSGP PPEA EQAW PQS |
| 遺伝子ID: | 29924 |
| Uniprot: | Q9Y6I3 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 94kDa |
 | Western blot - EPN1 Rabbit pAb (CAB17695) |
| 同義語: | EPN1 |
| バックグラウンド: | This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016] |
| UniProt Protein Function: | epsin 1: Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis. Belongs to the epsin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: plasma membrane Molecular Function:protein binding Biological Process: negative regulation of epidermal growth factor receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9Y6I3 |
| NCBI GenInfo Identifier: | 332278179 |
| NCBI Gene ID: | 29924 |
| NCBI Accession: | Q9Y6I3.2 |
| UniProt Secondary Accession: | Q9Y6I3,Q86ST3, Q9HA18, |
| UniProt Related Accession: | Q9Y6I3 |
| Molecular Weight: | 57,504 Da |
| NCBI Full Name: | Epsin-1 |
| NCBI Synonym Full Names: | epsin 1 |
| NCBI Official Symbol: | EPN1 |
| NCBI Protein Information: | epsin-1 |
| UniProt Protein Name: | Epsin-1 |
| UniProt Synonym Protein Names: | EH domain-binding mitotic phosphoprotein; EPS-15-interacting protein 1 |
| UniProt Gene Name: | EPN1 |
| UniProt Entry Name: | EPN1_HUMAN |