Anti-EPHB4 Antibody (CAB3293)
- SKU:
- CAB3293
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
| 抗体名: | Anti-EPHB4 Antibody |
| 抗体コード: | CAB3293 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4 (NP_004435.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4 (NP_004435.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AVCQ CRVG YFRA RTDP RGAP CTTP PSAP RSVV SRLN GSSL HLEW SAPL ESGG REDL TYAL RCRE CRPG GSCA PCGG DLTF DPGP RDLV EPWV VVRG LRPD FTYT FEVT ALNG VSSL ATGP VPFE PVNV TTDR EVPP AVSD IRVT RSSP SSLS LAWA VPRA PSGA VLDY EVKY HEKG AEGP SSVR FLKT SENR AELR GLKR GASY LVQV RARS EAGY GPFG QEHH SQTQ LDES EGWR EQLA L |
| 遺伝子ID: | 2050 |
| Uniprot: | P54760 |
| セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
| 計算された分子量: | 108kDa |
| 観察された分子量: | 108kDa |
| 同義語: | EPHB4, HFASD, HTK, MYK1, TYRO11 |
| バックグラウンド: | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |
| NCBI Summary: | Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P54760 |
| NCBI GenInfo Identifier: | 495473 |
| NCBI Gene ID: | 2050 |
| NCBI Accession: | |
| UniProt Related Accession: | P54760 |
| Molecular Weight: | |
| NCBI Full Name: | tyrosine kinase |
| NCBI Synonym Full Names: | EPH receptor B4 |
| NCBI Official Symbol: | EPHB4 |
| NCBI Official Synonym Symbols: | HTK; MYK1; HFASD; CMAVM2; LMPHM7; TYRO11 |
| NCBI Protein Information: | ephrin type-B receptor 4 |
| UniProt Protein Name: | |
| UniProt Gene Name: |
 | Western blot analysis of extracts of mouse liver, using EPHB4 antibody (CAB3293) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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