Anti-ENTPD6 抗体 (CAB15655)

抗体名:	Anti-ENTPD6 Antibody
抗体コード:	CAB15655
抗体サイズ:	20uL, 50uL, 100uL
申し込み:	WB IHC
反応性:	Human, Mouse, Rat
宿主種:	Rabbit
免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 61-300 of human ENTPD6 (NP_001304870.1).

申し込み:	WB IHC
推奨希釈:	WB 1:500 - 1:2000 IHC 1:100 - 1:200
反応性:	Human, Mouse, Rat
ポジティブサンプル:	Mouse brain, Mouse spleen, Rat brain, Rat spleen

免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 61-300 of human ENTPD6 (NP_001304870.1).
精製方法:	Affinity purification
ストレージバッファ:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:	IgG
順序:	WHRA TATQ AFFS ITRA APGA RWGQ QAHS PLGT AADG HEVF YGIM FDAG STGT RVHV FQFT RPPR ETPT LTHE TFKA LKPG LSAY ADDV EKSA QGIR ELLD VAKQ DIPF DFWK ATPL VLKA TAGL RLLP GEKA QKLL QKVK EVFK ASPF LVGD DCVS IMNG TDEG VSAW ITIN FLTG SLKT PGGS SVGM LDLG GGST QIAF LPRV EGTL QASP PGYL TALR MFNR TYKL YSYS YLGL GLMS
遺伝子ID:	955
Uniprot:	O75354
セルラーロケーション:	Golgi apparatus membrane, Secreted, Single-pass type II membrane protein
計算された分子量:	51kDa/53kDa
観察された分子量:	45kDa

同義語:	ENTPD6, CD39L2, IL-6SAG, IL6ST2, NTPDase-6, dJ738P15.3
バックグラウンド:	ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt Protein Function:	ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, integral; Hydrolase; EC 3.6.1.6 Chromosomal Location of Human Ortholog: 20p11.21 Cellular Component: Golgi membrane; extracellular space; cell surface; integral to membrane; plasma membrane Molecular Function:nucleoside-triphosphatase activity; guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity; uridine-diphosphatase activity Biological Process: response to magnesium ion; metabolic process; response to calcium ion
NCBI Summary:	ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which is characteristic of NTPases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	O75354
NCBI GenInfo Identifier:	317373443
NCBI Gene ID:	955
NCBI Accession:	O75354.3
UniProt Secondary Accession:	O75354,Q5QPJ2, Q5QPJ5, Q7Z5B5, Q8N3H3, Q8TAS7, Q9UJD1 A6NCX6, D3DW49,
UniProt Related Accession:	O75354
Molecular Weight:	53,118 Da
NCBI Full Name:	Ectonucleoside triphosphate diphosphohydrolase 6
NCBI Synonym Full Names:	ectonucleoside triphosphate diphosphohydrolase 6 (putative)
NCBI Official Symbol:	ENTPD6
NCBI Official Synonym Symbols:	CD39L2; IL6ST2; IL-6SAG; NTPDase-6; dJ738P15.3
NCBI Protein Information:	ectonucleoside triphosphate diphosphohydrolase 6; CD39 antigen-like 2; CD39-like 2; HCV-E2 binding protein 1; NTPDase 6; ectonucleoside triphosphate diphosphohydrolase 6 (putative function); interleukin 6 signal transducer-2
UniProt Protein Name:	Ectonucleoside triphosphate diphosphohydrolase 6
UniProt Synonym Protein Names:	CD39 antigen-like 2
Protein Family:	Ectonucleoside triphosphate diphosphohydrolase
UniProt Gene Name:	ENTPD6
UniProt Entry Name:	ENTP6_HUMAN

	Western blot analysis of extracts of various cell lines, using ENTPD6 antibody (CAB15655) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded rat brain using ENTPD6 antibody (CAB15655) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded human colon carcinoma using ENTPD6 antibody (CAB15655) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse spinal cord using ENTPD6 antibody (CAB15655) at dilution of 1:100 (40x lens).

Antibodies

ENTPD6 Antibody (PACO09104)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)