Anti-EN2 Antibody (CAB17480)
- SKU:
- CAB17480
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-EN2 Antibody |
| 抗体コード: | CAB17480 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of Human EN2. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Mouse brain, Rat brain |
| 免疫原: | A synthetic peptide of Human EN2. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2020 |
| Uniprot: | P19622 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 33kDa |
 | Western blot - EN2 Polyclonal Antibody (CAB17480) |
| 同義語: | EN2 |
| バックグラウンド: | Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | En-2: Genetic variations in EN2 may be associated with susceptibility to autism. Belongs to the engrailed homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 7q36 Cellular Component: nucleus Biological Process: multicellular organismal development Disease: Autism, Susceptibility To, 10 |
| NCBI Summary: | Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P19622 |
| NCBI GenInfo Identifier: | 21903415 |
| NCBI Gene ID: | 2020 |
| NCBI Accession: | P19622.3 |
| UniProt Secondary Accession: | P19622,Q549U3, Q9UD58, A4D252, |
| UniProt Related Accession: | P19622 |
| Molecular Weight: | 34,211 Da |
| NCBI Full Name: | Homeobox protein engrailed-2 |
| NCBI Synonym Full Names: | engrailed homeobox 2 |
| NCBI Official Symbol: | EN2 |
| NCBI Protein Information: | homeobox protein engrailed-2 |
| UniProt Protein Name: | Homeobox protein engrailed-2 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | EN2 |
| UniProt Entry Name: | HME2_HUMAN |