Anti-ELP3 Antibody (CAB9877)
- SKU:
- CAB9877
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Neuroscience
Frequently bought together:
Description
| 抗体名: | Anti-ELP3 Antibody |
| 抗体コード: | CAB9877 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 358-547 of human ELP3 (NP_060561.3). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 358-547 of human ELP3 (NP_060561.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PWTR VYRV QRDI PMPL VSSG VEHG NLRE LALA RMKD LGIQ CRDV RTRE VGIQ EIHH KVRP YQVE LVRR DYVA NGGW ETFL SYED PDQD ILIG LLRL RKCS EETF RFEL GGGV SIVR ELHV YGSV VPVS SRDP TKFQ HQGF GMLL MEEA ERIA REEH GSGK IAVI SGVG TRNY YRKI GYRL QGPY MVKM LK |
| 遺伝子ID: | 55140 |
| Uniprot: | Q9H9T3 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 49kDa/52kDa/60kDa/62kDa |
| 観察された分子量: | 62kDa |
| 同義語: | ELP3, KAT9 |
| バックグラウンド: |
| UniProt Protein Function: | ELP3: a histone acetyltransferase. A subunit of the Elongator complex, which associates with the elongating, hyperphosphorylated form of RNA polymerase II. |
| UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase Chromosomal Location of Human Ortholog: 8p21.1 Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleolus; transcription elongation factor complex Molecular Function:H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding Biological Process: central nervous system development; neuron migration; positive regulation of cell migration; regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; tRNA wobble uridine modification |
| NCBI Summary: | ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009] |
| UniProt Code: | Q9H9T3 |
| NCBI GenInfo Identifier: | 145558902 |
| NCBI Gene ID: | 55140 |
| NCBI Accession: | Q9H9T3.2 |
| UniProt Secondary Accession: | Q9H9T3,Q53G84, Q6AWB0, Q9BVF7, Q9NVZ1, B4DE19, B4DIG1 E2QRI5, |
| UniProt Related Accession: | Q9H9T3 |
| Molecular Weight: | 52,202 Da |
| NCBI Full Name: | Elongator complex protein 3 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 3 |
| NCBI Official Symbol: | ELP3 |
| NCBI Official Synonym Symbols: | KAT9 |
| NCBI Protein Information: | elongator complex protein 3 |
| UniProt Protein Name: | Elongator complex protein 3 |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP3 |
| UniProt Entry Name: | ELP3_HUMAN |
 | Western blot analysis of extracts of Mouse kidney, using ELP3 antibody (CAB9877) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 120s. |
 | Immunohistochemistry of paraffin-embedded rat cerebellum using ELP3 antibody (CAB9877) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse cerebellum using ELP3 antibody (CAB9877) at dilution of 1:100 (40x lens). |
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