Anti-ELOVL5 Antibody (CAB16567)
- SKU:
- CAB16567
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-ELOVL5 Antibody |
抗体コード: | CAB16567 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human ELOVL5 (NP_001229757.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 247-326 of human ELOVL5 (NP_001229757.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GVIW PCTF PLGW LYFQ IGYM ISLI ALFT NFYI QTYN KKGA SRRK DHLK DHQN GSMA AVNG HTNS FSPL ENNV KPRK LRKD |
遺伝子ID: | 60481 |
Uniprot: | Q9NYP7 |
セルラーロケーション: | Cell projection, Endoplasmic reticulum membrane, Multi-pass membrane protein, dendrite |
計算された分子量: | 9kDa/35kDa/38kDa |
観察された分子量: | 37kDa |
同義語: | ELOVL5, HELO1, SCA38, dJ483K16.1 |
バックグラウンド: | This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. |
UniProt Protein Function: | ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family. |
UniProt Protein Details: | Protein type:EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6p12.1 Cellular Component: cell soma; dendrite; endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane Molecular Function:fatty acid elongase activity; protein binding Biological Process: cellular lipid metabolic process; linoleic acid metabolic process; triacylglycerol biosynthetic process; unsaturated fatty acid biosynthetic process; unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process Disease: Spinocerebellar Ataxia 38 |
NCBI Summary: | This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q9NYP7 |
NCBI GenInfo Identifier: | 74753072 |
NCBI Gene ID: | 60481 |
NCBI Accession: | Q9NYP7.1 |
UniProt Secondary Accession: | Q9NYP7,Q59EL3, Q5TGH5, Q6NXE7, Q7L2S5, Q8NCG4, Q9UI22 B4DZJ2, F6SH78, |
UniProt Related Accession: | Q9NYP7 |
Molecular Weight: | 9,580 Da |
NCBI Full Name: | Elongation of very long chain fatty acids protein 5 |
NCBI Synonym Full Names: | ELOVL fatty acid elongase 5 |
NCBI Official Symbol: | ELOVL5 |
NCBI Official Synonym Symbols: | HELO1; SCA38; dJ483K16.1 |
NCBI Protein Information: | elongation of very long chain fatty acids protein 5 |
UniProt Protein Name: | Elongation of very long chain fatty acids protein 5 |
UniProt Synonym Protein Names: | 3-keto acyl-CoA synthase ELOVL5 |
UniProt Gene Name: | ELOVL5 |
UniProt Entry Name: | ELOV5_HUMAN |
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