Anti-ELF5 Antibody (CAB7181)
- SKU:
- CAB7181
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-ELF5 Antibody |
抗体コード: | CAB7181 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ELF5 (NP_001413.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Rat lung, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ELF5 (NP_001413.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLDS VTHS TFLP NASF CDPL MSWT DLFS NEEY YPAF EHQT ACDS YWTS VHPE YWTK RHVW EWLQ FCCD QYKL DTNC ISFC NFNI SGLQ LCSM TQEE FVEA AGLC GEYL YFIL QNIR TQGY SFFN DAEE SKAT IKDY ADSN CLKT SGIK SQDC HSHS RTSL QSSH LWEF VR |
遺伝子ID: | 2001 |
Uniprot: | Q9UKW6 |
セルラーロケーション: | Nucleus |
計算された分子量: | 16kDa/18kDa/30kDa/31kDa |
観察された分子量: | 31KDa |
同義語: | ELF5, ESE2 |
バックグラウンド: | The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
UniProt Protein Function: | ELF5: Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation. Belongs to the ETS family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 11p13-p12 Cellular Component: nucleus Biological Process: cell differentiation; cell proliferation; regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011] |
UniProt Code: | Q9UKW6 |
NCBI GenInfo Identifier: | 68565549 |
NCBI Gene ID: | 2001 |
NCBI Accession: | Q9UKW6.2 |
UniProt Secondary Accession: | Q9UKW6,O95175, Q8N2K9, Q96QY3, Q9UKW5, A6XAE6, A8K452 |
UniProt Related Accession: | Q9UKW6 |
Molecular Weight: | 18,866 Da |
NCBI Full Name: | ETS-related transcription factor Elf-5 |
NCBI Synonym Full Names: | E74 like ETS transcription factor 5 |
NCBI Official Symbol: | ELF5 |
NCBI Official Synonym Symbols: | ESE2 |
NCBI Protein Information: | ETS-related transcription factor Elf-5 |
UniProt Protein Name: | ETS-related transcription factor Elf-5 |
UniProt Synonym Protein Names: | E74-like factor 5; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2 |
Protein Family: | ETS-related transcription factor |
UniProt Gene Name: | ELF5 |
UniProt Entry Name: | ELF5_HUMAN |
View AllClose