Anti-EIF4EBP2 Antibody (CAB13691)
- SKU:
- CAB13691
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-EIF4EBP2 Antibody |
| 抗体コード: | CAB13691 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-120 of human EIF4EBP2 (NP_004087.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, Jurkat |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 61-120 of human EIF4EBP2 (NP_004087.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DRRN SPMA QTPP CHLP NIPG VTSP GTLI EDSK VEVN NLNN LNNH DRKH AVGD DAQF EMDI |
| 遺伝子ID: | 1979 |
| Uniprot: | Q13542 |
| セルラーロケーション: | |
| 計算された分子量: | 12kDa |
| 観察された分子量: | 16kDa |
| 同義語: | EIF4EBP2, 4EBP2, PHASII |
| バックグラウンド: | This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. |
| UniProt Protein Function: | 4E-BP2: eukaryotic translation initiation factor 4E binding protein 2 |
| UniProt Protein Details: | Protein type:Translation; Translation initiation Chromosomal Location of Human Ortholog: 10q21-q22 Cellular Component: cytoplasm Molecular Function:eukaryotic initiation factor 4E binding; protein binding; translation repressor activity Biological Process: cAMP-mediated signaling; insulin receptor signaling pathway; memory; negative regulation of translational initiation; regulation of synaptic plasticity; regulation of synaptic transmission; social behavior; TOR signaling pathway; translation |
| NCBI Summary: | This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q13542 |
| NCBI GenInfo Identifier: | 34921510 |
| NCBI Gene ID: | 1979 |
| NCBI Accession: | Q13542.1 |
| UniProt Related Accession: | Q13542 |
| Molecular Weight: | 12,939 Da |
| NCBI Full Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E binding protein 2 |
| NCBI Official Symbol: | EIF4EBP2 |
| NCBI Official Synonym Symbols: | 4EBP2; PHASII |
| NCBI Protein Information: | eukaryotic translation initiation factor 4E-binding protein 2 |
| UniProt Protein Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
| UniProt Gene Name: | EIF4EBP2 |
| UniProt Entry Name: | 4EBP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using EIF4EBP2 antibody (CAB13691) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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