Anti-EGFL7 Antibody (CAB9376)

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SKU:
CAB9376
Product type:
Antibody
Application:
WB
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cardiovascular
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Description

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抗体名:Anti-EGFL7 Antibody
抗体コード:CAB9376
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 24-100 of human EGFL7 (NP_958854.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Mouse, Rat
ポジティブサンプル:Mouse heart, Mouse lung, Mouse kidney, Rat spleen, Rat kidney
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 24-100 of human EGFL7 (NP_958854.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:YRPG RRVC AVRA HGDP VSES FVQR VYQP FLTT CDGH RACS TYRT IYRT AYRR SPGL APAR PRYA CCPG WKRT SGLP G
遺伝子ID:51162
Uniprot:Q9UHF1
セルラーロケーション:Secreted, extracellular space
計算された分子量:29kDa
観察された分子量:30kDa
同義語:EGFL7, NEU1, VE-STATIN, ZNEU1
バックグラウンド:This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:EGFL7: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.
UniProt Protein Details:

Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function:calcium ion binding; Notch binding

Biological Process: blood vessel development; negative regulation of Notch signaling pathway; positive regulation of endothelial cell proliferation; angiogenesis; cell adhesion; vasculogenesis; negative regulation of cell migration

NCBI Summary:This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
UniProt Code:Q9UHF1
NCBI GenInfo Identifier:92090985
NCBI Gene ID:51162
NCBI Accession:Q9UHF1.3
UniProt Secondary Accession:Q9UHF1,Q5M7Y5, Q5VUD5, Q96EG0, B3KRP0, M9VTX9,
UniProt Related Accession:Q9UHF1
Molecular Weight:29,618 Da
NCBI Full Name:Epidermal growth factor-like protein 7
NCBI Synonym Full Names:EGF-like-domain, multiple 7
NCBI Official Symbol:EGFL7  
NCBI Official Synonym Symbols:NEU1; ZNEU1; VE-STATIN  
NCBI Protein Information:epidermal growth factor-like protein 7; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7
UniProt Protein Name:Epidermal growth factor-like protein 7
UniProt Synonym Protein Names:Multiple epidermal growth factor-like domains protein 7; Multiple EGF-like domains protein 7; NOTCH4-like protein; Vascular endothelial statin; VE-statin; Zneu1
Protein Family:Epidermal growth factor-like protein
UniProt Gene Name:EGFL7  
UniProt Entry Name:EGFL7_HUMAN
Anti-EGFL7 Polyclonal Antibody (CAB9376)Western blot analysis of extracts of various cell lines, using EGFL7 antibody (CAB9376) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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