Anti-EDC3 Antibody (CAB13763)
- SKU:
- CAB13763
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-EDC3 Antibody |
| 抗体コード: | CAB13763 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 159-508 of human EDC3 (NP_079359.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, MCF7, HeLa, Mouse pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 159-508 of human EDC3 (NP_079359.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HNSW SSSS RHPN QATP KKSG LKNG QMKN KDDE CFGD DIEE IPDT DFDF EGNL ALFD KAAV FEEI DTYE RRSG TRSR GIPN ERPT RYRH DENI LESE PIVY RRII VPHN VSKE FCTD SGLV VPSI SYEL HKKL LSVA EKHG LTLE RRLE MTGV CASQ MALT LLGG PNRL NPKN VHQR PTVA LLCG PHVK GAQG ISCG RHLA NHDV QVIL FLPN FVKM LESI TNEL SLFS KTQG QQVS SLKD LPTS PVDL VINC LDCP ENVF LRDQ PWYK AAVA WANQ NRAP VLSI DPPV HEVE QGID AKWS LALG LPLP LGEH AGRI YLCD IGIP QQVF QEVG INYH SPFG CKFV IPLH SA |
| 遺伝子ID: | 80153 |
| Uniprot: | Q96F86 |
| セルラーロケーション: | Cytoplasm, P-body |
| 計算された分子量: | 56kDa |
| 観察された分子量: | 56kDa |
| 同義語: | EDC3, LSM16, MRT50, YJDC, YJEFN2 |
| バックグラウンド: |
| UniProt Protein Function: | EDC3: Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis. Belongs to the EDC3 family. |
| UniProt Protein Details: | Protein type:RNA processing Chromosomal Location of Human Ortholog: 15q24.1 Cellular Component: membrane; cytosol Molecular Function:identical protein binding; protein binding; RNA binding Biological Process: gene expression; mRNA catabolic process, deadenylation-dependent decay Disease: Mental Retardation, Autosomal Recessive 50 |
| NCBI Summary: | EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96F86 |
| NCBI GenInfo Identifier: | 74731669 |
| NCBI Gene ID: | 80153 |
| NCBI Accession: | Q96F86.1 |
| UniProt Secondary Accession: | Q96F86,Q9H797, B3KPH0, D3DW61, |
| UniProt Related Accession: | Q96F86 |
| Molecular Weight: | 508 |
| NCBI Full Name: | Enhancer of mRNA-decapping protein 3 |
| NCBI Synonym Full Names: | enhancer of mRNA decapping 3 |
| NCBI Official Symbol: | EDC3 |
| NCBI Official Synonym Symbols: | YJDC; LSM16; YJEFN2 |
| NCBI Protein Information: | enhancer of mRNA-decapping protein 3; yjeF_N2; hYjeF_N2; hYjeF_N2-15q23; yjeF domain containing; yjeF domain-containing protein 1; LSM16 homolog (EDC3, S. cerevisiae); enhancer of mRNA decapping 3 homolog; yjeF N-terminal domain-containing protein 2 |
| UniProt Protein Name: | Enhancer of mRNA-decapping protein 3 |
| UniProt Synonym Protein Names: | LSM16 homolog; YjeF N-terminal domain-containing protein 2; YjeF_N2; hYjeF_N2; YjeF domain-containing protein 1 |
| Protein Family: | Enhancer of mRNA-decapping protein |
| UniProt Gene Name: | EDC3 |
| UniProt Entry Name: | EDC3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using EDC3 antibody (CAB13763) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat brain using EDC3 antibody (CAB13763) at dilution of 1:150 (40x lens). |
View AllClose