Anti-ECI2 Antibody (CAB13072)
- SKU:
- CAB13072
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ECI2 Antibody |
| 抗体コード: | CAB13072 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human ECI2 (NP_006108.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human ECI2 (NP_006108.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MNRT AMRA SQKD FENS MNQV KLLK KDPG NEVK LKLY ALYK QATE GPCN MPKP GVFD LINK AKWD AWNA LGSL PKEA ARQN YVDL VSSL SPSL ESSS QVEP GTDR KSTG FETL VVTS EDGI TKIM FNRP KKKN AINT EMYH EIMR ALKA ASKD DSII TVLT GNGD YYSS GNDL TNFT DIPP GGVE EKAK NNAV LLRE FVGC FIDF PKPL IAVV NGPA VGIS VTLL GLFD AVYA SDRA TFHT PFSH LGQS PEGC SSYT FPKI MSPA KATE MLIF GKKL TAGE ACAQ GLVT EVFP DSTF QKEV WTRL KAFA KLPP NALR ISKE VIRK RERE KLHA VNAE ECNV LQGR WLSD ECTN AVVN FLSR KSKL |
| 遺伝子ID: | 10455 |
| Uniprot: | O75521 |
| セルラーロケーション: | Mitochondrion, Peroxisome matrix |
| 計算された分子量: | 39kDa/43kDa |
| 観察された分子量: | 55kDa |
| 同義語: | ECI2, ACBD2, DRS-1, DRS1, HCA88, PECI, dJ1013A10.3 |
| バックグラウンド: | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | PECI: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Isomerase; EC 5.3.3.8; Lipid Metabolism - fatty acid Chromosomal Location of Human Ortholog: 6p24.3 Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; nucleoplasm; peroxisomal matrix Molecular Function:dodecenoyl-CoA delta-isomerase activity; receptor binding Biological Process: cellular lipid metabolic process |
| NCBI Summary: | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011] |
| UniProt Code: | O75521 |
| NCBI GenInfo Identifier: | 257051079 |
| NCBI Gene ID: | 10455 |
| NCBI Accession: | O75521.4 |
| UniProt Secondary Accession: | O75521,Q5JYK5, Q5JYK7, Q7L124, Q8N0X0, Q9BUE9, Q9H0T9 Q9NQH1, Q9NYH7, Q9UN55, |
| UniProt Related Accession: | O75521 |
| Molecular Weight: | 39,609 Da |
| NCBI Full Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
| NCBI Synonym Full Names: | enoyl-CoA delta isomerase 2 |
| NCBI Official Symbol: | ECI2 |
| NCBI Official Synonym Symbols: | DRS1; PECI; ACBD2; DRS-1; HCA88; dJ1013A10.3 |
| NCBI Protein Information: | enoyl-CoA delta isomerase 2, mitochondrial |
| UniProt Protein Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
| UniProt Synonym Protein Names: | DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hepatocellular carcinoma-associated antigen 88; Peroxisomal 3,2-trans-enoyl-CoA isomerase; pECI; Renal carcinoma antigen NY-REN-1 |
| Protein Family: | Enoyl-CoA delta isomerase |
| UniProt Gene Name: | ECI2 |
| UniProt Entry Name: | ECI2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ECI2 Rabbit pAb (CAB13072) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using ECI2 antibody (CAB13072) at dilution of 1:150 (40x lens). |
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