Anti-DYNLT3 Antibody (CAB16982)
- SKU:
- CAB16982
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-DYNLT3 Antibody |
| 抗体コード: | CAB16982 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DEVG FNAE EAHN IVKE CVDG VLGG EDYN HNNI NQWT ASIV EQSL THLV KLGK AYKY IVTC AVVQ KSAY GFHT ASSC FWDT TSDG TCTV RWE |
| 遺伝子ID: | 6990 |
| Uniprot: | P51808 |
| セルラーロケーション: | |
| 計算された分子量: | 13kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | DYNLT3, RP3, TCTE1L, TCTEX1L |
| バックグラウンド: | This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20. |
| UniProt Protein Function: | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. |
| NCBI Summary: | This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010] |
| UniProt Code: | P51808 |
| NCBI GenInfo Identifier: | 5730087 |
| NCBI Gene ID: | 6990 |
| NCBI Accession: | NP_006511.1 |
| UniProt Secondary Accession: | P51808,Q6ICS3, |
| UniProt Related Accession: | P51808 |
| Molecular Weight: | 12 |
| NCBI Full Name: | dynein light chain Tctex-type 3 |
| NCBI Synonym Full Names: | dynein light chain Tctex-type 3 |
| NCBI Official Symbol: | DYNLT3 |
| NCBI Official Synonym Symbols: | RP3; TCTE1L; TCTEX1L |
| NCBI Protein Information: | dynein light chain Tctex-type 3 |
| UniProt Protein Name: | Dynein light chain Tctex-type 3 |
| UniProt Synonym Protein Names: | Protein 91/23; T-complex-associated testis-expressed 1-like |
| UniProt Gene Name: | DYNLT3 |
 | Western blot analysis of extracts of various cell lines, using DYNLT3 antibody (CAB16982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |