Anti-DYNLL2 Antibody (CAB13888)
- SKU:
- CAB13888
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-DYNLL2 Antibody |
| 抗体コード: | CAB13888 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_542408.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, A-431, Mouse brain, Mouse heart, Mouse kidney, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_542408.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSDR KAVI KNAD MSED MQQD AVDC ATQA MEKY NIEK DIAA YIKK EFDK KYNP TWHC IVGR NFGS YVTH ETKH FIYF YLGQ VAIL LFKS G |
| 遺伝子ID: | 140735 |
| Uniprot: | Q96FJ2 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 10kDa |
| 観察された分子量: | 12kDa |
| 同義語: | DYNLL2, DNCL1B, Dlc2, RSPH22 |
| バックグラウンド: |
| UniProt Protein Function: | DYNLL2: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Belongs to the dynein light chain family. |
| UniProt Protein Details: | Protein type:Microtubule-binding; Motility/polarity/chemotaxis; Motor Chromosomal Location of Human Ortholog: 17q22 Cellular Component: dynein complex; microtubule; centrosome; membrane; plasma membrane; myosin complex; cytosol; nucleus Molecular Function:protein binding; cytoskeletal protein binding; motor activity Biological Process: metabolic process; transport; apoptosis; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule-based process; synaptic target recognition |
| UniProt Code: | Q96FJ2 |
| NCBI GenInfo Identifier: | 56748850 |
| NCBI Gene ID: | 140735 |
| NCBI Accession: | Q96FJ2.1 |
| UniProt Secondary Accession: | Q96FJ2,B2R5B4, |
| UniProt Related Accession: | Q96FJ2 |
| Molecular Weight: | 10,350 Da |
| NCBI Full Name: | Dynein light chain 2, cytoplasmic |
| NCBI Synonym Full Names: | dynein, light chain, LC8-type 2 |
| NCBI Official Symbol: | DYNLL2 |
| NCBI Official Synonym Symbols: | Dlc2; DNCL1B; RSPH22 |
| NCBI Protein Information: | dynein light chain 2, cytoplasmic; 8 kDa dynein light chain b; DLC8b; radial spoke 22 homolog |
| UniProt Protein Name: | Dynein light chain 2, cytoplasmic |
| UniProt Synonym Protein Names: | 8 kDa dynein light chain b; DLC8b; Dynein light chain LC8-type 2 |
| Protein Family: | Dynein |
| UniProt Gene Name: | DYNLL2 |
| UniProt Entry Name: | DYL2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DYNLL2 antibody (CAB13888) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunofluorescence analysis of NIH/3T3 cells using DYNLL2 antibody (CAB13888) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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