Anti-DSTYK Antibody (CAB9870)
- SKU:
- CAB9870
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DSTYK Antibody |
| 抗体コード: | CAB9870 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 635-884 of human DSTYK (NP_955749.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | 293T, HeLa, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 635-884 of human DSTYK (NP_955749.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RLSL ESCS LQDV LLHR KPKL GQEL GRGQ YGVV YLCD NWGG HFPC ALKS VVPP DEKH WNDL ALEF HYMR SLPK HERL VDLH GSVI DYNY GGGS SIAV LLIM ERLH RDLY TGLK AGLT LETR LQIA LDVV EGIR FLHS QGLV HRDI KLKN VLLD KQNR AKIT DLGF CKPE AMMS GSIV GTPI HMAP ELFT GARP ERLP VFDE ECWQ LMEA CWDG DPLK RPLL GIVQ PMLQ GIMN RLCK SNSE QPNR GLDD ST |
| 遺伝子ID: | 25778 |
| Uniprot: | Q6XUX3 |
| セルラーロケーション: | Apical cell membrane, Basolateral cell membrane, Cell junction, Cell membrane, Cytoplasm |
| 計算された分子量: | 20kDa/66kDa/99kDa/105kDa |
| 観察された分子量: | 105kDa |
| 同義語: | DSTYK, CAKUT1, DustyPK, HDCMD38P, RIP5, RIPK5, SPG23 |
| バックグラウンド: | This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | DSTYK: a serine/threonine protein kinase of the 'Other-Unique' family, most closely related to kinases of the TKL family including IRAK and RIPK. Overexpression induces apoptotic cell death. The caspase inhibitor crmA apparently blocks DNA fragmentation but not apoptosis, suggesting that SgK496 may induce both caspase-dependent apoptosis and caspase-independent cell death. Four alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Protein kinase, Other; EC 2.7.12.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Motility/polarity/chemotaxis; Other group; Other-Unique family Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: apical plasma membrane; basolateral plasma membrane; cell junction; cytoplasm; cytosol Molecular Function:ATP binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein-tyrosine kinase activity Biological Process: peptidyl-tyrosine phosphorylation; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of kinase activity Disease: Congenital Anomalies Of Kidney And Urinary Tract, Susceptibility To |
| NCBI Summary: | This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. It is thought to function as a regulator of cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q6XUX3 |
| NCBI GenInfo Identifier: | 296434486 |
| NCBI Gene ID: | 25778 |
| NCBI Accession: | Q6XUX3.2 |
| UniProt Secondary Accession: | Q6XUX3,O75060, Q17R94, Q5RKT0, Q6IN87, Q6P997, Q86Y03 Q9P1S5, B7ZL64, |
| UniProt Related Accession: | Q6XUX3 |
| Molecular Weight: | |
| NCBI Full Name: | Dual serine/threonine and tyrosine protein kinase |
| NCBI Synonym Full Names: | dual serine/threonine and tyrosine protein kinase |
| NCBI Official Symbol: | DSTYK |
| NCBI Official Synonym Symbols: | RIP5; RIPK5; CAKUT1; DustyPK; HDCMD38P |
| NCBI Protein Information: | dual serine/threonine and tyrosine protein kinase |
| UniProt Protein Name: | Dual serine/threonine and tyrosine protein kinase |
| UniProt Synonym Protein Names: | Dusty protein kinase; Dusty PK; RIP-homologous kinase; Receptor-interacting serine/threonine-protein kinase 5; Sugen kinase 496; SgK496 |
| UniProt Gene Name: | DSTYK |
| UniProt Entry Name: | DUSTY_HUMAN |
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