Anti-DSG4 Antibody (CAB10502)
- SKU:
- CAB10502
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DSG4 Antibody |
| 抗体コード: | CAB10502 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse pancreas, Rat pancreas, A-375, DU145, BxPC-3, Mouse pancreas, Mouse small intestine |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-630 of human DSG4 (NP_817123.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TGTI CIEV PDIN DYCP NIFP ERRT ICID SPSV LISV NEHS YGSP FTFC VVDE PPGI ADMW DVRS TNAT SAIL TAKQ VLSP GFYE IPIL VKDS YNRA CELA QMVQ LYAC DCDD NHMC LDSG AAGI YTED ITGD TYGP VTED QAGV SNVG LGP |
| 遺伝子ID: | 147409 |
| Uniprot: | Q86SJ6 |
| セルラーロケーション: | Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome |
| 計算された分子量: | 113kDa/115kDa |
| 観察された分子量: | 114kDa |
| 同義語: | DSG4, CDGF13, CDHF13, HYPT6, LAH |
| バックグラウンド: | This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes. |
| NCBI Summary: | This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth. [provided by RefSeq, May 2016] |
| UniProt Code: | Q86SJ6 |
| NCBI GenInfo Identifier: | 60389774 |
| NCBI Gene ID: | 147409 |
| NCBI Accession: | Q86SJ6.1 |
| UniProt Secondary Accession: | Q86SJ6,Q6Y9L9, Q8IXV4, A2RUI1, |
| UniProt Related Accession: | Q86SJ6 |
| Molecular Weight: | 114kDa |
| NCBI Full Name: | Desmoglein-4 |
| NCBI Synonym Full Names: | desmoglein 4 |
| NCBI Official Symbol: | DSG4 |
| NCBI Official Synonym Symbols: | LAH; HYPT6; CDGF13; CDHF13 |
| NCBI Protein Information: | desmoglein-4 |
| UniProt Protein Name: | Desmoglein-4 |
| UniProt Synonym Protein Names: | Cadherin family member 13 |
| Protein Family: | Desmoglein |
| UniProt Gene Name: | DSG4 |
 | Western blot analysis of extracts of various cell lines, using DSG4 antibody (CAB10502) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Western blot analysis of extracts of various cell lines, using DSG4 antibody (CAB10502) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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