Anti-DPYSL3 Antibody (CAB12280)
- SKU:
- CAB12280
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DPYSL3 Antibody |
| 抗体コード: | CAB12280 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DPYSL3 (NP_001184223.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DPYSL3 (NP_001184223.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MASG RRGW DSSH EDDL PVYL ARPG TTDQ VPRQ KYGG MFCN VEGA FESK TLDF DALS VGQR GAKT PRSG QGSD RGSG SRPG IEGD TPRR GQGR EESR EPAP ASPA PAGV EIRS ATGK EVLQ NLGP KDKS DRLL IKGG RIVN DDQS FYAD IYME DGLI KQIG DNLI VPGG VKTI EANG KMVI PGGI DVHT HFQM PYKG MTTV DDFF QGTK AALA GGTT MIID HVVP EPES SLTE AYEK WREW ADGK SCCD YALH VDIT HWND SVKQ EVQN LIKD KGVN SFMV |
| 遺伝子ID: | 1809 |
| Uniprot: | Q14195 |
| セルラーロケーション: | Cell projection, Cytoplasm, growth cone |
| 計算された分子量: | 61kDa/73kDa |
| 観察された分子量: | 62KDa |
| 同義語: | DPYSL3, CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1 |
| バックグラウンド: |
| UniProt Protein Function: | CRMP-4: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Hydrolase Chromosomal Location of Human Ortholog: 5q32 Cellular Component: filamentous actin; extracellular space; growth cone; lamellipodium; cytosol Molecular Function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; phosphoprotein binding; SH3 domain binding Biological Process: actin crosslink formation; positive regulation of filopodium formation; actin filament bundle formation; axon guidance; response to axon injury; negative regulation of cell migration; pyrimidine base catabolic process; protein homooligomerization |
| UniProt Code: | Q14195 |
| NCBI GenInfo Identifier: | 3122050 |
| NCBI Gene ID: | 1809 |
| NCBI Accession: | Q14195.1 |
| UniProt Secondary Accession: | Q14195,Q93012, B3SXQ8, |
| UniProt Related Accession: | Q14195 |
| Molecular Weight: | 570 |
| NCBI Full Name: | Dihydropyrimidinase-related protein 3 |
| NCBI Synonym Full Names: | dihydropyrimidinase-like 3 |
| NCBI Official Symbol: | DPYSL3 |
| NCBI Official Synonym Symbols: | DRP3; ULIP; CRMP4; DRP-3; LCRMP; CRMP-4; ULIP-1 |
| NCBI Protein Information: | dihydropyrimidinase-related protein 3; unc-33-like phosphoprotein 1; collapsin response mediator protein 4 long |
| UniProt Protein Name: | Dihydropyrimidinase-related protein 3 |
| UniProt Synonym Protein Names: | Collapsin response mediator protein 4; CRMP-4; Unc-33-like phosphoprotein 1; ULIP-1 |
| Protein Family: | Dihydropyrimidinase-related protein |
| UniProt Gene Name: | DPYSL3 |
| UniProt Entry Name: | DPYL3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DPYSL3 Polyclonal Antibody (CAB12280) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min. |
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