| UniProt Protein Function: | As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. |
| NCBI Summary: | This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q9C005 |
| NCBI GenInfo Identifier: | 14211889 |
| NCBI Gene ID: | 84661 |
| NCBI Accession: | NP_115963.1 |
| UniProt Secondary Accession: | Q9C005,D6W578, |
| UniProt Related Accession: | Q9C005 |
| Molecular Weight: | 11,250 Da |
| NCBI Full Name: | protein dpy-30 homolog isoform 1 |
| NCBI Synonym Full Names: | dpy-30, histone methyltransferase complex regulatory subunit |
| NCBI Official Symbol: | DPY30 |
| NCBI Official Synonym Symbols: | Cps25; Saf19; HDPY-30 |
| NCBI Protein Information: | protein dpy-30 homolog |
| UniProt Protein Name: | Protein dpy-30 homolog |
| UniProt Synonym Protein Names: | Dpy-30-like protein; Dpy-30L |
| Protein Family: | DPY30 domain-containing protein |
| UniProt Gene Name: | DPY30 |
