Anti-DPP10 Antibody (CAB16563)
- SKU:
- CAB16563
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DPP10 Antibody |
| 抗体コード: | CAB16563 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPP10 (NP_001308842.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | U-251MG |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPP10 (NP_001308842.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GYIA SMIL KSDE KLFK CGSV VAPI TDLK LYAS AFSE RYLG MPSK EEST YQAA SVLH NVHG LKEE NILI IHGT ADTK VHFQ HSAE LIKH LIKA GVNY TMQV Y |
| 遺伝子ID: | 57628 |
| Uniprot: | Q8N608 |
| セルラーロケーション: | Cell membrane, Single-pass type II membrane protein |
| 計算された分子量: | 85kDa/90kDa/91kDa |
| 観察された分子量: | 110kDa |
| 同義語: | DPP10, DPL2, DPPY, DPRP-3, DPRP3 |
| バックグラウンド: | This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| UniProt Protein Function: | Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155). |
| NCBI Summary: | This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N608 |
| NCBI GenInfo Identifier: | 296434483 |
| NCBI Gene ID: | 57628 |
| NCBI Accession: | Q8N608.2 |
| UniProt Secondary Accession: | Q8N608,Q0GLB8, Q53QT3, Q53S86, Q53SL8, Q53SS4, Q6TTV4 Q86YR9, Q9P236, A8K1Q2, J3KPP2, J3KQ46, |
| UniProt Related Accession: | Q8N608 |
| Molecular Weight: | 85,480 Da |
| NCBI Full Name: | Inactive dipeptidyl peptidase 10 |
| NCBI Synonym Full Names: | dipeptidyl peptidase like 10 |
| NCBI Official Symbol: | DPP10 |
| NCBI Official Synonym Symbols: | DPL2; DPPY; DPRP3; DPRP-3 |
| NCBI Protein Information: | inactive dipeptidyl peptidase 10 |
| UniProt Protein Name: | Inactive dipeptidyl peptidase 10 |
| UniProt Synonym Protein Names: | Dipeptidyl peptidase IV-related protein 3; DPRP-3; Dipeptidyl peptidase X; DPP X; Dipeptidyl peptidase-like protein 2; DPL2 |
| Protein Family: | Inactive dipeptidyl peptidase |
| UniProt Gene Name: | DPP10 |
| UniProt Entry Name: | DPP10_HUMAN |
 | Western blot analysis of extracts of U-251MG cells, using DPP10 antibody (CAB16563) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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