Anti-DNAJC7 Antibody (CAB2780)
- SKU:
- CAB2780
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DNAJC7 Antibody |
| 抗体コード: | CAB2780 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-431, 293T, K-562 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human DNAJC7 (NP_003306.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VQFF VQAL RMAP DHEK ACIA CRNA KALK AKKE DGNK AFKE GNYK LAYE LYTE ALGI DPNN IKTN AKLY CNRG TVNS KLRK LDDA IEDC TNAV KLDD TYIK AYLR RAQC YMDT EQYE EAVR DYEK VYQT EKTK EHKQ LLKN AQLE LKKS KRK |
| 遺伝子ID: | 7266 |
| Uniprot: | Q99615 |
| セルラーロケーション: | Cytoplasm, Nucleus, cytoskeleton |
| 計算された分子量: | 50kDa/56kDa |
| 観察された分子量: | 60kDa |
| 同義語: | DNAJC7, DJ11, DJC7, TPR2, TTC2 |
| バックグラウンド: | This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | DNAJC7: a co-chaperone protein that binds both Hsp70 and Hsp90 through its TPR domains. Its DnaJ domain stimulates ATP hydrolysis and polypeptide binding by Hsp70. Interacts with the proapoptotic and cell-cycle checkpoint protein Rad9. Rad9 transiently dissociates from Tpr2 following heat-shock or UV treatments. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 17q21.2 Cellular Component: nucleoplasm; cytoskeleton; membrane; cytoplasm Molecular Function:protein binding; heat shock protein binding Biological Process: protein folding |
| NCBI Summary: | This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the chaperone proteins heat shock proteins 70 and 90 in an ATP-dependent manner and may function as a co-chaperone. Pseudogenes of this gene are found on chromosomes 1 and 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q99615 |
| NCBI GenInfo Identifier: | 46397879 |
| NCBI Gene ID: | 7266 |
| NCBI Accession: | Q99615.2 |
| UniProt Related Accession: | Q99615 |
| Molecular Weight: | 60kDa |
| NCBI Full Name: | DnaJ homolog subfamily C member 7 |
| NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member C7 |
| NCBI Official Symbol: | DNAJC7 |
| NCBI Official Synonym Symbols: | DJ11; DJC7; TPR2; TTC2 |
| NCBI Protein Information: | dnaJ homolog subfamily C member 7 |
| UniProt Protein Name: | DnaJ homolog subfamily C member 7 |
| UniProt Synonym Protein Names: | Tetratricopeptide repeat protein 2; TPR repeat protein 2 |
| Protein Family: | DnaJ homolog subfamily |
| UniProt Gene Name: | DNAJC7 |
| UniProt Entry Name: | DNJC7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DNAJC7 antibody (CAB2780) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
View AllClose