Anti-DNAJA2 Antibody (CAB7059)
- SKU:
- CAB7059
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DNAJA2 Antibody |
| 抗体コード: | CAB7059 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 233-412 of human DNAJA2 (NP_005871.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-375, 293T, HepG2, MCF7, Mouse kidney, Mouse heart, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 233-412 of human DNAJA2 (NP_005871.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FTGE ADQA PGVE PGDI VLLL QEKE HEVF QRDG NDLH MTYK IGLV EALC GFQF TFKH LDGR QIVV KYPP GKVI EPGC VRVV RGEG MPQY RNPF EKGD LYIK FDVQ FPEN NWIN PDKL SELE DLLP SRPE VPNI IGET EEVE LQEF DSTR GSGG GQRR EAYN DSSD EESS SHHG PGVQ CAHQ |
| 遺伝子ID: | 10294 |
| Uniprot: | O60884 |
| セルラーロケーション: | Lipid-anchor, Membrane |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 46kDa |
| 同義語: | DNAJA2, CPR3, DJ3, DJA2, DNAJ, DNJ3, HIRIP4, PRO3015, RDJ2 |
| バックグラウンド: | The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. |
| UniProt Protein Function: | DNAJA2: Co-chaperone of Hsc70. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Chaperone Chromosomal Location of Human Ortholog: 16q12.1 Cellular Component: membrane; cytosol Molecular Function:protein binding; heat shock protein binding; metal ion binding; chaperone binding; unfolded protein binding; ATP binding Biological Process: response to heat; positive regulation of cell proliferation; protein refolding |
| NCBI Summary: | The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60884 |
| NCBI GenInfo Identifier: | 14916548 |
| NCBI Gene ID: | 10294 |
| NCBI Accession: | O60884.1 |
| UniProt Secondary Accession: | O60884,O14711, B2R7L7, |
| UniProt Related Accession: | O60884 |
| Molecular Weight: | 412 |
| NCBI Full Name: | DnaJ homolog subfamily A member 2 |
| NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| NCBI Official Symbol: | DNAJA2 |
| NCBI Official Synonym Symbols: | DJ3; CPR3; DJA2; DNAJ; DNJ3; RDJ2; HIRIP4; PRO3015 |
| NCBI Protein Information: | dnaJ homolog subfamily A member 2; HIRA interacting protein 4; HIRA-interacting protein 4; cell cycle progression 3 protein; renal carcinoma antigen NY-REN-14; cell cycle progression restoration gene 3 protein |
| UniProt Protein Name: | DnaJ homolog subfamily A member 2 |
| UniProt Synonym Protein Names: | Cell cycle progression restoration gene 3 protein; Dnj3; Dj3; HIRA-interacting protein 4; Renal carcinoma antigen NY-REN-14 |
| Protein Family: | DnaJ homolog subfamily |
| UniProt Gene Name: | DNAJA2 |
| UniProt Entry Name: | DNJA2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DNAJA2 antibody (CAB7059) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunofluorescence analysis of C6 cells using DNAJA2 antibody (CAB7059) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of NIH/3T3 cells using DNAJA2 antibody (CAB7059) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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