Anti-DMKN Antibody (CAB13871)
- SKU:
- CAB13871
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DMKN Antibody |
| 抗体コード: | CAB13871 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 355-449 of human DMKN (NP_001177276.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 355-449 of human DMKN (NP_001177276.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | WEDF KQNT PFLN WKAI IEGA DASS LQKR AGRA DQPG AGWQ EVAA VTSK NYNY NQHA YPTA YGGK YSVK TPAK GGVS PSSS ASRV QPGL LQWV KFW |
| 遺伝子ID: | 93099 |
| Uniprot: | Q6E0U4 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 9kDa/14-20kDa/35-47kDa |
| 観察された分子量: | 47kDa |
| 同義語: | DMKN, UNQ729, ZD52F10, dermokine |
| バックグラウンド: | This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| UniProt Protein Function: | DMKN: May act as a soluble regulator of keratinocyte differentiation (Potential). Belongs to the dermokine family. 15 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19q13.12 Cellular Component: extracellular space Molecular Function:protein binding |
| NCBI Summary: | This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010] |
| UniProt Code: | Q6E0U4 |
| NCBI GenInfo Identifier: | 290457677 |
| NCBI Gene ID: | 93099 |
| NCBI Accession: | Q6E0U4.3 |
| UniProt Secondary Accession: | Q6E0U4,Q32W58, Q32W62, Q32W63, A3EZ79, A3EZ80, A3EZ81 A3EZ82, A3EZ83, C9J4P6, C9J5N8, C9JAL3, |
| UniProt Related Accession: | Q6E0U4 |
| Molecular Weight: | 46,944 Da |
| NCBI Full Name: | Dermokine |
| NCBI Synonym Full Names: | dermokine |
| NCBI Official Symbol: | DMKN |
| NCBI Official Synonym Symbols: | UNQ729; ZD52F10 |
| NCBI Protein Information: | dermokine; epidermis-specific secreted protein SK30/SK89 |
| UniProt Protein Name: | Dermokine |
| UniProt Synonym Protein Names: | Epidermis-specific secreted protein SK30/SK89 |
| Protein Family: | Dermokine |
| UniProt Gene Name: | DMKN |
| UniProt Entry Name: | DMKN_HUMAN |
 | Western blot analysis of extracts of rat ovary, using DMKN antibody (CAB13871) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
View AllClose