Anti-DLX1 Antibody (CAB17381)
- SKU:
- CAB17381
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| 抗体名: | Anti-DLX1 Antibody |
| 抗体コード: | CAB17381 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MTMT TMPE SLNS PVSG KAVF MEFG PPNQ QMSP SPMS HGHY SMHC LHSA GHSQ PDGA YSSA SSFS RPLG YPYV NSVS SHAS SPYI SSVQ SYPG SASL AQSR LEDP GADS EKST VVEG GEVR |
| 遺伝子ID: | 1745 |
| Uniprot: | P56177 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | DLX1 |
| バックグラウンド: | This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. |
| NCBI Summary: | This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P56177 |
| NCBI GenInfo Identifier: | 84043956 |
| NCBI Gene ID: | 1745 |
| NCBI Accession: | NP_001033582.1 |
| UniProt Secondary Accession: | P56177,Q53ZU4, Q7Z724, Q8IYB2, D3DPD7, |
| UniProt Related Accession: | P56177 |
| Molecular Weight: | |
| NCBI Full Name: | homeobox protein DLX-1 isoform 2 |
| NCBI Synonym Full Names: | distal-less homeobox 1 |
| NCBI Official Symbol: | DLX1 |
| NCBI Protein Information: | homeobox protein DLX-1 |
| UniProt Protein Name: | Homeobox protein DLX-1 |
| Protein Family: | Homeobox protein |
| UniProt Gene Name: | DLX1 |
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