Anti-DLGAP2 Antibody (CAB13818)

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SKU:
CAB13818
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

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抗体名:Anti-DLGAP2 Antibody
抗体コード:CAB13818
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human DLGAP2 (NP_004736.2).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human
ポジティブサンプル:U-87MG, 293T
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human DLGAP2 (NP_004736.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:TAQS STES TQDA YQDS RAQR MSPW PQDS RGLY NSTD SLDS NKAM NLAL ETAA AQRH LPES QSSS VRTS DKAI LVSK AEEL LKSR CSSI GIQD SEFP EHQP YPRS DVET ATDS DTES RGLR EYHS VGVQ VEDE KRHG RFKR SNSV TAAV QADL ELEG FPGH ITTE DKGL QFGS SFQR HSEP STPT QYSA VRTV RTQG LFSY REDY RTQV DTST LPPP DPWL EPAI DTVE TGRM SPCR RDGS WFLK LLHA ETK
遺伝子ID:9228
Uniprot:Q9P1A6
セルラーロケーション:Cell junction, Cell membrane, Peripheral membrane protein, postsynaptic cell membrane, postsynaptic density, synapse
計算された分子量:108kDa/115kDa/117kDa
観察された分子量:117kDa
同義語:DLGAP2, C8orf68, DAP2, ERICH1-AS1, SAPAP2
バックグラウンド:The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified.
UniProt Protein Function:SAPAP2: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Belongs to the SAPAP family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Kinase, other

Chromosomal Location of Human Ortholog: 8p23

Cellular Component: postsynaptic membrane; postsynaptic density; neurofilament; cell junction

Molecular Function:protein binding

Biological Process: nerve-nerve synaptic transmission

NCBI Summary:The product of this gene is a membrane-associated protein that may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2014]
UniProt Code:Q9P1A6
NCBI GenInfo Identifier:160395585
NCBI Gene ID:9228
NCBI Accession:Q9P1A6.4
UniProt Secondary Accession:Q9P1A6,O14488, O14664, Q9P1A7, A1QCF8, A1QCF9, A5D8Y2
UniProt Related Accession:Q9P1A6
Molecular Weight:
NCBI Full Name:Disks large-associated protein 2
NCBI Synonym Full Names:discs, large (Drosophila) homolog-associated protein 2
NCBI Official Symbol:DLGAP2  
NCBI Official Synonym Symbols:DAP2; SAPAP2  
NCBI Protein Information:disks large-associated protein 2; PSD-95/SAP90-binding protein 2; discs large-associated protein 2; SAP90/PSD-95-associated protein 2
UniProt Protein Name:Disks large-associated protein 2
UniProt Synonym Protein Names:PSD-95/SAP90-binding protein 2; SAP90/PSD-95-associated protein 2; SAPAP2
Protein Family:Disks large-associated protein
UniProt Gene Name:DLGAP2  
UniProt Entry Name:DLGP2_HUMAN
Anti-DLGAP2 Antibody (CAB13818)Western blot analysis of extracts of various cell lines, using DLGAP2 antibody (CAB13818) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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