Anti-DHX9 Antibody (CAB17955)
- SKU:
- CAB17955
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-DHX9 Antibody |
| 抗体コード: | CAB17955 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human DHX9 |
| 申し込み: | WB IF IP |
| 推奨希釈: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 IP 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Mouse thymus, Mouse brain, Rat brain |
| 免疫原: | Recombinant protein of human DHX9 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 1660 |
| Uniprot: | Q08211 |
| セルラーロケーション: | Cytoplasm, Nucleus, nucleolus |
| 計算された分子量: | 24kDa/140kDa |
| 観察された分子量: | 140kDa |
 | Western blot - DHX9 Rabbit pAb (CAB17955) |
| 同義語: | DHX9, DDX9, LKP, NDH2, NDHII, RHA |
| バックグラウンド: | This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13. |
| UniProt Protein Function: | DDX9: a helicase that unwinds double-stranded DNA and RNA in a 3' to 5' direction. Interacts with the RNA-induced silencing complex (RISC) in human cells and functions in RISC loading. Generates multiple secondary structures that influence RNA-binding proteins. Has a dsRNA binding motif at the N-terminus, RGG-box at the carboxyl terminus, and a bidirectional nuclear transport domain of 110 amino acids at the carboxyl terminus. May play a role in X-linked gene expression. |
| UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Spliceosome; Nucleolus; Helicase; RNA splicing; EC 3.6.4.13; RNA-binding; RNA processing Chromosomal Location of Human Ortholog: 1q25 Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; nucleolus; nucleus; ribonucleoprotein complex; cytosol Molecular Function:ATP-dependent DNA helicase activity; protein binding; DNA binding; ATP-dependent RNA helicase activity; ATP binding; RNA helicase activity Biological Process: osteoblast differentiation; circadian rhythm; RNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing; positive regulation of interferon type I production; innate immune response; gene expression; DNA duplex unwinding |
| NCBI Summary: | This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010] |
| UniProt Code: | Q08211 |
| NCBI GenInfo Identifier: | 116241330 |
| NCBI Gene ID: | 1660 |
| NCBI Accession: | Q08211.4 |
| UniProt Related Accession: | Q08211 |
| Molecular Weight: | 141kDa |
| NCBI Full Name: | ATP-dependent RNA helicase A |
| NCBI Synonym Full Names: | DExH-box helicase 9 |
| NCBI Official Symbol: | DHX9 |
| NCBI Official Synonym Symbols: | LKP; RHA; DDX9; NDH2; NDHII |
| NCBI Protein Information: | ATP-dependent RNA helicase A |
| UniProt Protein Name: | ATP-dependent RNA helicase A |
| UniProt Synonym Protein Names: | DEAH box protein 9; Leukophysin; LKP; Nuclear DNA helicase II; NDH II |
| UniProt Gene Name: | DHX9 |
| UniProt Entry Name: | DHX9_HUMAN |