Anti-DHX30 Antibody (CAB8575)
- SKU:
- CAB8575
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DHX30 Antibody |
| 抗体コード: | CAB8575 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 906-1155 of human DHX30 (NP_055781.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, Jurkat, LO2, MCF7, Mouse eye, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 906-1155 of human DHX30 (NP_055781.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GWEE VLRW QDRS SREN YLEE NLLY APSL RFIH GLIK QFSE NIYE AFLV GKPS DCTL ASAQ CNEY SEEE ELVK GVLM AGLY PNLI QVRQ GKVT RQGK FKPN SVTY RTKS GNIL LHKS TINR EATR LRSR WLTY FMAV KSNG SVFV RDSS QVHP LAVL LLTD GDVH IRDD GRRA TISL SDSD LLRL EGDS RTVR LLKE LRRA LGRM VERS LRSE LAAL PPSV QEEH GQLL ALLA ELLR GPCG SFDV RKTA DD |
| 遺伝子ID: | 22907 |
| Uniprot: | Q7L2E3 |
| セルラーロケーション: | Cytoplasm, Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid |
| 計算された分子量: | 129kDa/133kDa/136kDa |
| 観察された分子量: | 129kDa |
| 同義語: | DHX30, DDX30, RETCOR |
| バックグラウンド: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | DDX30: Required for optimal function of the zinc-finger antiviral protein ZC3HAV1. Associates with mitochondrial DNA. Belongs to the DEAD box helicase family. DEAH subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Helicase; RNA-binding; Nuclear receptor co-regulator; EC 3.6.4.13 Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: cytoplasm; mitochondrion; nucleus Molecular Function:ATP-dependent RNA helicase activity; chromatin binding; double-stranded RNA binding; protein binding Biological Process: RNA processing |
| NCBI Summary: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013] |
| UniProt Code: | Q7L2E3 |
| NCBI GenInfo Identifier: | 74758997 |
| NCBI Gene ID: | 22907 |
| NCBI Accession: | Q7L2E3.1 |
| UniProt Secondary Accession: | Q7L2E3,O94965, Q7Z753, Q96CH4, Q9NUQ0, A8K5F1, |
| UniProt Related Accession: | Q7L2E3 |
| Molecular Weight: | 129,438 Da |
| NCBI Full Name: | Putative ATP-dependent RNA helicase DHX30 |
| NCBI Synonym Full Names: | DEAH-box helicase 30 |
| NCBI Official Symbol: | DHX30 |
| NCBI Official Synonym Symbols: | DDX30; RETCOR |
| NCBI Protein Information: | putative ATP-dependent RNA helicase DHX30 |
| UniProt Protein Name: | Putative ATP-dependent RNA helicase DHX30 |
| UniProt Synonym Protein Names: | DEAH box protein 30 |
| Protein Family: | Putative ATP-dependent RNA helicase |
| UniProt Gene Name: | DHX30 |
| UniProt Entry Name: | DHX30_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DHX30 antibody (CAB8575) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |