Anti-DHRS4 Antibody (CAB10285)
- SKU:
- CAB10285
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DHRS4 Antibody |
| 抗体コード: | CAB10285 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human DHRS4 (NP_066284.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, LO2, A-549, MCF7, SW620, Mouse liver, Mouse lung, Mouse small intestine, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-278 of human DHRS4 (NP_066284.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MHKA GLLG LCAR AWNS VRMA SSGM TRRD PLAN KVAL VTAS TDGI GFAI ARRL AQDG AHVV VSSR KQQN VDQA VATL QGEG LSVT GTVC HVGK AEDR ERLV ATAV KLHG GIDI LVSN AAVN PFFG SIMD VTEE VWDK TLDI NVKA PALM TKAV VPEM EKRG GGSV VIVS SIAA FSPS PGFS PYNV SKTA LLGL TKTL AIEL APRN IRVN CLAP GLIK TSFS RMLW MDKE KEES MKET LRIR RLGE PEDC AGIV SFLC SEDA SYIT GETV VVGG GTPS RL |
| 遺伝子ID: | 10901 |
| Uniprot: | Q9BTZ2 |
| セルラーロケーション: | Nucleus, Peroxisome |
| 計算された分子量: | 8kDa/16kDa/20kDa/21kDa/23kDa/25kDa/29kDa |
| 観察された分子量: | 30kDa |
| 同義語: | DHRS4, CR, NRDR, PHCR, PSCD, SCAD-SRL, SDR-SRL, SDR25C1, SDR25C2 |
| バックグラウンド: |
| UniProt Protein Function: | DHRS4: Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.1.1.184; Cofactor and Vitamin Metabolism - retinol Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: peroxisomal membrane; endoplasmic reticulum membrane; nuclear membrane; mitochondrion; intracellular membrane-bound organelle; peroxisome; nucleus Molecular Function:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; alcohol dehydrogenase [NAD(P)+] activity; 3-keto sterol reductase activity; carbonyl reductase (NADPH) activity; receptor binding Biological Process: steroid metabolic process; ketone metabolic process; alcohol metabolic process; protein tetramerization |
| UniProt Code: | Q9BTZ2 |
| NCBI GenInfo Identifier: | 308153604 |
| NCBI Gene ID: | 10901 |
| NCBI Accession: | Q9BTZ2.3 |
| UniProt Secondary Accession: | Q9BTZ2,O95162, Q20CR0, Q2LC19, Q2LE81, Q58IU4, Q6E0Y1 Q6UWU3, B2RB10, B7WNS9, D3YTB8, E2QRL8, |
| UniProt Related Accession: | Q9BTZ2 |
| Molecular Weight: | 23,917 Da |
| NCBI Full Name: | Dehydrogenase/reductase SDR family member 4 |
| NCBI Synonym Full Names: | dehydrogenase/reductase (SDR family) member 4 |
| NCBI Official Symbol: | DHRS4 |
| NCBI Official Synonym Symbols: | CR; NRDR; PHCR; PSCD; SDR-SRL; SDR25C1; SDR25C2; SCAD-SRL |
| NCBI Protein Information: | dehydrogenase/reductase SDR family member 4; peroxisomal short-chain alcohol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; short-chain dehydrogenase/reductase family member 4; dehydrogenase/reductase (SDR family) member 4 like 2A; short chain dehydrogenase/reductase family 25C, member 1; short chain dehydrogenase/reductase family 25C, member 2; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase |
| UniProt Protein Name: | Dehydrogenase/reductase SDR family member 4 |
| UniProt Synonym Protein Names: | NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short-chain dehydrogenase/reductase family member 4 |
| UniProt Gene Name: | DHRS4 |
| UniProt Entry Name: | DHRS4_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DHRS4 antibody (CAB10285) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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