Anti-DHDH Antibody (CAB6577)
- SKU:
- CAB6577
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DHDH Antibody |
| 抗体コード: | CAB6577 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human DHDH (NP_055290.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse liver, Mouse skin, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human DHDH (NP_055290.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MALR WGIV SVGL ISSD FTAV LQTL PRSE HQVV AVAA RDLS RAKE FAQK HDIP KAYG SYEE LAKD PSVE VAYI GTQH PQHK AAVM LCLA AGKA VLCE KPTG VNAA EVRE MVAE ARSR ALFL MEAI WTRF FPAS EALR SVLA QGTL GDLR VARA EFGK NLIH VPRA VDRA QAGG ALLD IGIY CVQF TSMV FGGQ KPEK ISVV GRRH ETGV DDTV TVLL QYPG EVHG SFTC SITV QLSN TASV SGTK GMVQ LLNP CWCP TELV VKGE HKEF PLPP VPKD CNFD NGAG MSYE AKHV WECL RKGM KESP VIPL SESE LLAD ILEE VRKA IGVT FPQD KR |
| 遺伝子ID: | 27294 |
| Uniprot: | Q9UQ10 |
| セルラーロケーション: | |
| 計算された分子量: | 36kDa |
| 観察された分子量: | 36kDa |
| 同義語: | DHDH, 2DD, HUM2DD |
| バックグラウンド: | This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. |
| UniProt Protein Function: | DHDH: an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:EC 1.3.1.20; EC 1.1.1.179; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase Chromosomal Location of Human Ortholog: 19q13.3 Molecular Function:NAD(P) transhydrogenase activity; electron carrier activity; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; D-xylose 1-dehydrogenase (NADP+) activity Biological Process: carbohydrate metabolic process; D-xylose catabolic process |
| NCBI Summary: | This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UQ10 |
| NCBI GenInfo Identifier: | 74735193 |
| NCBI Gene ID: | 27294 |
| NCBI Accession: | Q9UQ10.1 |
| UniProt Related Accession: | Q9UQ10 |
| Molecular Weight: | 334 |
| NCBI Full Name: | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
| NCBI Synonym Full Names: | dihydrodiol dehydrogenase (dimeric) |
| NCBI Official Symbol: | DHDH |
| NCBI Official Synonym Symbols: | 2DD; HUM2DD |
| NCBI Protein Information: | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; 3-deoxyglucosone reductase; D-xylose-NADP dehydrogenase |
| UniProt Protein Name: | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
| UniProt Synonym Protein Names: | D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase (EC:1.1.1.179); Dimeric dihydrodiol dehydrogenase; Hum2DD |
| Protein Family: | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase |
| UniProt Gene Name: | DHDH |
| UniProt Entry Name: | DHDH_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DHDH Antibody (CAB6577) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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