Anti-DGKE Antibody (CAB7752)
- SKU:
- CAB7752
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-DGKE Antibody |
抗体コード: | CAB7752 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human DGKE (NP_003638.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse |
ポジティブサンプル: | MCF7, HeLa, 293T, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-260 of human DGKE (NP_003638.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | CSLQ RSRR QLHR RDIF RKSK HGWR DTDL FSQP TYCC VCAQ HILQ GAFC DCCG LRVD EGCL RKAD KRFQ CKEI MLKN DTKV LDAM PHHW IRGN VPLC SYCM VCKQ QCGC QPKL CDYR CIWC QKTV HDEC MKNS LKNE KCDF GEFK NLII PPSY LTSI NQMR KDKK TDYE VLAS KLGK QWTP LIIL ANSR SGTN MGEG LLGE FRIL LNPV QVFD VTKT PPIK A |
遺伝子ID: | 8526 |
Uniprot: | P52429 |
セルラーロケーション: | Cytoplasm, Membrane, Multi-pass membrane protein |
計算された分子量: | 20kDa/63kDa |
観察された分子量: | 64kDa |
同義語: | DGKE, AHUS7, DAGK5, DAGK6, DGK, NPHS7 |
バックグラウンド: | Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. |
UniProt Protein Function: | DGKE: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. Belongs to the eukaryotic diacylglycerol kinase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.7.1.107; Motility/polarity/chemotaxis; Kinase, lipid Chromosomal Location of Human Ortholog: 17q22 Cellular Component: membrane; cytoplasm; integral to membrane; plasma membrane Molecular Function:metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; phospholipid biosynthetic process Disease: Nephrotic Syndrome, Type 7 |
NCBI Summary: | Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P52429 |
NCBI GenInfo Identifier: | 4503313 |
NCBI Gene ID: | 8526 |
NCBI Accession: | NP_003638.1 |
UniProt Related Accession: | P52429 |
Molecular Weight: | ~ 64kDa |
NCBI Full Name: | diacylglycerol kinase epsilon |
NCBI Synonym Full Names: | diacylglycerol kinase epsilon |
NCBI Official Symbol: | DGKE |
NCBI Official Synonym Symbols: | DGK; AHUS7; DAGK5; DAGK6; NPHS7 |
NCBI Protein Information: | diacylglycerol kinase epsilon |
UniProt Protein Name: | Diacylglycerol kinase epsilon |
UniProt Synonym Protein Names: | Diglyceride kinase epsilon |
Protein Family: | Deoxyguanosine kinase |
UniProt Gene Name: | DGKE |
UniProt Entry Name: | DGKE_HUMAN |
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