Anti-DGCR2 Antibody (CAB14267)
- SKU:
- CAB14267
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DGCR2 Antibody |
| 抗体コード: | CAB14267 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-200 of human DGCR2 (NP_005128.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-200 of human DGCR2 (NP_005128.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | TEPL RPEL RCNP GQFA CRSG TIQC IPLP WQCD GWAT CEDE SDEA NCPE VTGE VRPH HGKE AVDP RQGR ARGG DPSH FHAV NVAQ PVRF SSFL GKCP TGWH HYEG TASC YRVY LSGE NYWD AAQT CQRL NGSL ATFS TDQE LRFV LAQE WDQP ERSF GWKD QRKL WVGY QYVI TGRN RSLE |
| 遺伝子ID: | 9993 |
| Uniprot: | P98153 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 36kDa/56kDa/60kDa |
| 観察された分子量: | 61kDa |
| 同義語: | DGCR2, DGS-C, IDD, LAN, SEZ-12 |
| バックグラウンド: | Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | DGCR2: Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 22q11.21 Biological Process: cognition; organ morphogenesis Disease: Velocardiofacial Syndrome |
| NCBI Summary: | Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| UniProt Code: | P98153 |
| NCBI GenInfo Identifier: | 1708396 |
| NCBI Gene ID: | 9993 |
| NCBI Accession: | P98153.1 |
| UniProt Secondary Accession: | P98153,A6NIB5, A8K6K5, B5TY34, B7Z935, |
| UniProt Related Accession: | P98153 |
| Molecular Weight: | 36,713 Da |
| NCBI Full Name: | Integral membrane protein DGCR2/IDD |
| NCBI Synonym Full Names: | DiGeorge syndrome critical region gene 2 |
| NCBI Official Symbol: | DGCR2 |
| NCBI Official Synonym Symbols: | IDD; LAN; DGS-C; SEZ-12 |
| NCBI Protein Information: | integral membrane protein DGCR2/IDD |
| UniProt Protein Name: | Integral membrane protein DGCR2/IDD |
| Protein Family: | Integral membrane protein |
| UniProt Gene Name: | DGCR2 |
| UniProt Entry Name: | IDD_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DGCR2 antibody (CAB14267) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
View AllClose