Anti-DEPDC6 Antibody (CAB9447)
- SKU:
- CAB9447
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DEPDC6 Antibody |
| 抗体コード: | CAB9447 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DEPDC6 (NP_073620.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, HepG2, MCF7 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DEPDC6 (NP_073620.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEEG GSTG SAGS DSST SGSG GAQQ RELE RMAE VLVT GEQL RLRL HEEK VIKD RRHH LKTY PNCF VAKE LIDW LIEH KEAS DRET AIKL MQKL ADRG IIHH VCDE HKEF KDVK LFYR FRKD DGTF PLDN EVKA FMRG QRLY EKLM SPEN TLLQ PREE EGVK YERT FMAS EFLD WLVQ EGEA TTRK EAEQ LCHR LMEH GIIQ HVSN KHPF VDSN LLYQ FRMN |
| 遺伝子ID: | 64798 |
| Uniprot: | Q8TB45 |
| セルラーロケーション: | |
| 計算された分子量: | 34kDa/46kDa |
| 観察された分子量: | 48KDa |
| 同義語: | DEPTOR, DEP.6, DEPDC6 |
| バックグラウンド: |
| UniProt Protein Function: | DEPTOR: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 8q24.12 Cellular Component: cytoplasm; intracellular Molecular Function:protein binding Biological Process: negative regulation of cell size; negative regulation of protein kinase activity; negative regulation of TOR signaling pathway |
| UniProt Code: | Q8TB45 |
| NCBI GenInfo Identifier: | 251757257 |
| NCBI Gene ID: | 64798 |
| NCBI Accession: | Q8TB45.2 |
| UniProt Secondary Accession: | Q8TB45,Q96EQ1, Q9H0R7, Q9H894, Q9HA07, B2RCL9, B4DN97 E7EV87, |
| UniProt Related Accession: | Q8TB45 |
| Molecular Weight: | 34,006 Da |
| NCBI Full Name: | DEP domain-containing mTOR-interacting protein |
| NCBI Synonym Full Names: | DEP domain containing MTOR interacting protein |
| NCBI Official Symbol: | DEPTOR |
| NCBI Official Synonym Symbols: | DEP.6; DEPDC6 |
| NCBI Protein Information: | DEP domain-containing mTOR-interacting protein |
| UniProt Protein Name: | DEP domain-containing mTOR-interacting protein |
| UniProt Synonym Protein Names: | DEP domain-containing protein 6 |
| Protein Family: | DEP domain-containing mTOR-interacting protein |
| UniProt Gene Name: | DEPTOR |
 | Western blot analysis of extracts of various cell lines, using DEPDC6 Rabbit pAb (CAB9447) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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