Anti-DDX6 Antibody (CAB9634)
- SKU:
- CAB9634
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-DDX6 Antibody |
抗体コード: | CAB9634 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human DDX6 |
申し込み: | WB IF |
推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, C2C12 |
免疫原: | A synthesized peptide derived from human DDX6 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 1656 |
Uniprot: | P26196 |
セルラーロケーション: | |
計算された分子量: | 54kDa |
観察された分子量: | 54KDa |
同義語: | HLR2, P54, RCK |
バックグラウンド: | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
UniProt Protein Function: | DDX6: an oncogenic ATP-dependent helicase of the DEAD box family. Interacts with argonaute proteins, Ago1 and Ago2, and is a general repressor of translation in human cells by miRNA-induced gene silencing. In the process of mRNA degradation, may play a role in mRNA decapping. |
UniProt Protein Details: | Protein type:RNA processing; Oncoprotein; EC 3.6.4.13; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: intracellular membrane-bound organelle; membrane; stress granule; cytoplasm; cytosol Molecular Function:protein domain specific binding; protein binding; helicase activity; ATP binding; RNA helicase activity Biological Process: gene expression; cytoplasmic mRNA processing body assembly; mRNA catabolic process, deadenylation-dependent decay |
NCBI Summary: | This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] |
UniProt Code: | P26196 |
NCBI GenInfo Identifier: | 116241327 |
NCBI Gene ID: | 1656 |
NCBI Accession: | P26196.2 |
UniProt Secondary Accession: | P26196,P54823, |
UniProt Related Accession: | P26196 |
Molecular Weight: | 483 |
NCBI Full Name: | Probable ATP-dependent RNA helicase DDX6 |
NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
NCBI Official Symbol: | DDX6 |
NCBI Official Synonym Symbols: | P54; RCK; HLR2 |
NCBI Protein Information: | probable ATP-dependent RNA helicase DDX6; DEAD box-6; oncogene RCK; DEAD box protein 6; ATP-dependent RNA helicase p54; DEAD (Asp-Glu-Ala-Asp) box polypeptide 6; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD) |
UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX6 |
UniProt Synonym Protein Names: | ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK |
UniProt Gene Name: | DDX6 |
UniProt Entry Name: | DDX6_HUMAN |
View AllClose