Anti-DDX21 Antibody (CAB7034)
- SKU:
- CAB7034
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-DDX21 Antibody |
| 抗体コード: | CAB7034 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 624-783 of human DDX21 (NP_004719.2). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | SW620, MCF7, HepG2, 293T, Mouse spleen, Mouse thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 624-783 of human DDX21 (NP_004719.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VDQR SLIN SNVG FVTM ILQC SIEM PNIS YAWK ELKE QLGE EIDS KVKG MVFL KGKL GVCF DVPT ASVT EIQE KWHD SRRW QLSV ATEQ PELE GPRE GYGG FRGQ REGS RGFR GQRD GNRR FRGQ REGS RGPR GQRS GGGN KSNR SQNK GQKR SFSK AFGQ |
| 遺伝子ID: | 9188 |
| Uniprot: | Q9NR30 |
| セルラーロケーション: | Nucleus, nucleolus, nucleoplasm |
| 計算された分子量: | 79kDa/87kDa |
| 観察された分子量: | 100kDa |
| 同義語: | DDX21, GUA, GURDB, RH-II/GU, RH-II/GuA |
| バックグラウンド: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. |
| UniProt Protein Function: | DDX21: a protein of the DEAD box helicase family. Unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. |
| UniProt Protein Details: | Protein type:EC 3.6.4.13; RNA processing; Helicase; Nucleolus; RNA-binding Chromosomal Location of Human Ortholog: 10q21 Cellular Component: membrane; nucleolus; nucleus Molecular Function:double-stranded RNA binding; ATP-dependent RNA helicase activity; ATP binding Biological Process: osteoblast differentiation; response to exogenous dsRNA; metabolic process; response to virus |
| NCBI Summary: | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NR30 |
| NCBI GenInfo Identifier: | 76803555 |
| NCBI Gene ID: | 9188 |
| NCBI Accession: | Q9NR30.5 |
| UniProt Secondary Accession: | Q9NR30,Q13436, Q5VX41, Q68D35, B2RDL0, |
| UniProt Related Accession: | Q9NR30 |
| Molecular Weight: | 783 |
| NCBI Full Name: | Nucleolar RNA helicase 2 |
| NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box helicase 21 |
| NCBI Official Symbol: | DDX21 |
| NCBI Official Synonym Symbols: | GUA; GURDB; RH-II/GU; RH-II/GuA |
| NCBI Protein Information: | nucleolar RNA helicase 2; RH II/Gu; gu-alpha; Gu protein; DEAD box protein 21; RNA helicase II/Gu alpha; nucleolar RNA helicase Gu; nucleolar RNA helicase II; DEAD (Asp-Glu-Ala-Asp) box polypeptide 21; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21 |
| UniProt Protein Name: | Nucleolar RNA helicase 2 |
| UniProt Synonym Protein Names: | DEAD box protein 21; Gu-alpha; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu |
| Protein Family: | Nucleolar RNA helicase |
| UniProt Gene Name: | DDX21 |
| UniProt Entry Name: | DDX21_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DDX21 antibody (CAB7034) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human kidney cancer using DDX21 antibody (CAB7034) at dilution of 1:100 (40x lens). |
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