Anti-DBP Antibody (CAB15270)
- SKU:
- CAB15270
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DBP Antibody |
| 抗体コード: | CAB15270 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | LO2, HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-325 of human DBP (NP_001343.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MARP VSDR TPAP LLLG GPAG TPPG GGAL LGLR SLLQ GTSK PKEP ASCL LKEK ERKA ALPA ATTP GPGL ETAG PADA PAGA VVGG GSPR GRPG PVPA PGLL APLL WERT LPFG DVEY VDLD AFLL EHGL PPSP PPPG GPSP EPSP ARTP APSP GPGS CGSA SPRS SPGH APAR AALG TASG HRAG LTSR DTPS PVDP DTVE VLMT FEPD PADL ALSS IPGH ETFD PRRH RFSE EELK PQPI MKKA RKIQ VPEE QKDE KYWS RRYK NNEA AKRS RDAR RLKE NQIS VRAA FLEK ENAL LRQE VVAV RQEL SHYR AVLS RYQA QHGA L |
| 遺伝子ID: | 1628 |
| Uniprot: | Q10586 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 34kDa |
| 観察された分子量: | 36kDa |
| 同義語: | DBP, DABP |
| バックグラウンド: | The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. |
| UniProt Protein Function: | DBP: This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. Belongs to the bZIP family. PAR subfamily. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 19q13.3 Biological Process: positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q10586 |
| NCBI GenInfo Identifier: | 1706312 |
| NCBI Gene ID: | 1628 |
| NCBI Accession: | Q10586.1 |
| UniProt Secondary Accession: | Q10586,A2I2P4, |
| UniProt Related Accession: | Q10586 |
| Molecular Weight: | 34,349 Da |
| NCBI Full Name: | D site-binding protein |
| NCBI Synonym Full Names: | D-box binding PAR bZIP transcription factor |
| NCBI Official Symbol: | DBP |
| NCBI Official Synonym Symbols: | DABP |
| NCBI Protein Information: | D site-binding protein |
| UniProt Protein Name: | D site-binding protein |
| UniProt Synonym Protein Names: | Albumin D box-binding protein; Albumin D-element-binding protein; Tax-responsive enhancer element-binding protein 302; TaxREB302 |
| Protein Family: | D site-binding protein |
| UniProt Gene Name: | DBP |
| UniProt Entry Name: | DBP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DBP antibody (CAB15270) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15S. |