Anti-DAPK2 Antibody (CAB8199)
- SKU:
- CAB8199
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | DAPK2 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8199 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human DAPK2 (NP_055141.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human DAPK2 (NP_055141.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VVNL ENFR KQYV RRRW KLSF SIVS LCNH LTRS LMKK VHLR PDED LRNC ESDT EEDI ARRK ALHP RRRS STS |
| 遺伝子ID: | 23604 |
| Uniprot: | Q9UIK4 |
| セルラーロケーション: | Cytoplasm, Cytoplasmic vesicle, autophagosome lumen |
| 計算された分子量: | 42kDa/55kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | DAPK2, DRP-1, DRP1 |
| バックグラウンド: | This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. |
| UniProt Protein Function: | DAPK2: an ubiquitously expressed protein kinase of the DAPK family. Activated by Ca(2+)/calmodulin. Contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain. Overexpression induces apoptosis. Expressed at high levels in heart, lung and skeletal muscle. |
| UniProt Protein Details: | Protein type:Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; CAMK group; DAPK family Chromosomal Location of Human Ortholog: 15q22.31 Cellular Component: cytoplasm Molecular Function:ATP binding; calmodulin binding; identical protein binding; protein binding; protein serine/threonine kinase activity Biological Process: anoikis; apoptosis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of autophagy |
| NCBI Summary: | This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UIK4 |
| NCBI GenInfo Identifier: | 38605084 |
| NCBI Gene ID: | 23604 |
| NCBI Accession: | Q9UIK4.1 |
| UniProt Secondary Accession: | Q9UIK4,O75892, Q24JS1, E9JGM7, |
| UniProt Related Accession: | Q9UIK4 |
| Molecular Weight: | 55,931 Da |
| NCBI Full Name: | Death-associated protein kinase 2 |
| NCBI Synonym Full Names: | death associated protein kinase 2 |
| NCBI Official Symbol: | DAPK2 |
| NCBI Official Synonym Symbols: | DRP1; DRP-1 |
| NCBI Protein Information: | death-associated protein kinase 2 |
| UniProt Protein Name: | Death-associated protein kinase 2 |
| UniProt Synonym Protein Names: | DAP-kinase-related protein 1; DRP-1 |
| Protein Family: | Death-associated protein kinase |
| UniProt Gene Name: | DAPK2 |
| UniProt Entry Name: | DAPK2_HUMAN |
 | Immunofluorescence analysis of U2OS cells using DAPK2 antibody (CAB8199) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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