Anti-Cytokeratin 10 Antibody (CAB4669)
- SKU:
- CAB4669
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BCIE
- Synonyms:
- BIE
- Synonyms:
- CK10
- Synonyms:
- EHK
- Synonyms:
- K10
- Synonyms:
- KPP
Frequently bought together:
Description
| 抗体名: | Cytokeratin 10 Rabbit mAb |
| 抗体コード: | CAB4669 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | BCIE, BIE, CK10, EHK, K10, KPP |
| 申し込み: | WB, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Cytokeratin 10 |
| 申し込み: | WB, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, A-431 |
| 免疫原: | A synthesized peptide derived from human Cytokeratin 10 |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 3858 |
| Uniprot: | P13645 |
| 計算された分子量: | 60kDa |
| 観察された分子量: | 60KDa |
| UniProt Protein Function: | K10: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K1. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 17q21 Cellular Component: cytoplasm; extracellular space; membrane; nucleus Biological Process: keratinocyte differentiation Disease: Epidermolytic Hyperkeratosis; Erythroderma, Ichthyosiform, Congenital Reticular; Ichthyosis, Cyclic, With Epidermolytic Hyperkeratosis |
| NCBI Summary: | This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P13645 |
| NCBI GenInfo Identifier: | 269849769 |
| NCBI Gene ID: | 3858 |
| NCBI Accession: | P13645.6 |
| UniProt Secondary Accession: | P13645,Q14664, Q8N175, |
| UniProt Related Accession: | P13645 |
| Molecular Weight: | 58,827 Da |
| NCBI Full Name: | Keratin, type I cytoskeletal 10 |
| NCBI Synonym Full Names: | keratin 10 |
| NCBI Official Symbol: | KRT10 |
| NCBI Official Synonym Symbols: | BIE; EHK; K10; KPP; BCIE; CK10 |
| NCBI Protein Information: | keratin, type I cytoskeletal 10 |
| UniProt Protein Name: | Keratin, type I cytoskeletal 10 |
| UniProt Synonym Protein Names: | Cytokeratin-10; CK-10; Keratin-10; K10 |
| Protein Family: | Keratin |
| UniProt Gene Name: | KRT10 |
| UniProt Entry Name: | K1C10_HUMAN |