Anti-CXCL10 Antibody (CAB1457)
- SKU:
- CAB1457
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
抗体名: | Anti-CXCL10 Antibody |
抗体コード: | CAB1457 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-98 of human CXCL10 (NP_001556.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-98 of human CXCL10 (NP_001556.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QGVP LSRT VRCT CISI SNQP VNPR SLEK LEII PASQ FCPR VEII ATMK KKGE KRCL NPES KAIK NLLK AVSK ERSK RSP |
遺伝子ID: | 3627 |
Uniprot: | P02778 |
セルラーロケーション: | Secreted |
計算された分子量: | 10kDa |
観察された分子量: | 11kDa |
同義語: | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 |
バックグラウンド: | This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. |
UniProt Protein Function: | CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family. |
UniProt Protein Details: | Protein type:Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space; extracellular region; external side of plasma membrane Molecular Function:heparin binding; protein binding; CXCR3 chemokine receptor binding; chemokine activity; cAMP-dependent protein kinase regulator activity; receptor binding Biological Process: muscle development; blood circulation; protein secretion; positive regulation of leukocyte chemotaxis; positive regulation of cAMP metabolic process; signal transduction; chemotaxis; regulation of cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of angiogenesis; response to vitamin D; cell surface receptor linked signal transduction; cell-cell signaling; positive regulation of cell proliferation; response to gamma radiation; positive regulation of transcription from RNA polymerase II promoter; immune response; positive regulation of release of sequestered calcium ion into cytosol; response to cold; negative regulation of myoblast differentiation; inflammatory response; regulation of protein kinase activity; defense response to virus |
NCBI Summary: | This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014] |
UniProt Code: | P02778 |
NCBI GenInfo Identifier: | 21542456 |
NCBI Gene ID: | 3627 |
NCBI Accession: | P02778.2 |
UniProt Secondary Accession: | P02778,Q96QJ5, |
UniProt Related Accession: | P02778 |
Molecular Weight: | 10,881 Da |
NCBI Full Name: | C-X-C motif chemokine 10 |
NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 10 |
NCBI Official Symbol: | CXCL10 |
NCBI Official Synonym Symbols: | C7; IFI10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10 |
NCBI Protein Information: | C-X-C motif chemokine 10; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10 |
UniProt Protein Name: | C-X-C motif chemokine 10 |
UniProt Synonym Protein Names: | 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10Cleaved into the following chain:CXCL10(1-73) |
UniProt Gene Name: | CXCL10 |
UniProt Entry Name: | CXL10_HUMAN |