Anti-CTRB1 Antibody (CAB15043)
- SKU:
- CAB15043
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CTRB1 Antibody |
| 抗体コード: | CAB15043 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 79-263 of human CTRB1 (NP_001897.4). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse spleen, Mouse stomach |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 79-263 of human CTRB1 (NP_001897.4). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RTSD VVVA GEFD QGSD EENI QVLK IAKV FKNP KFSI LTVN NDIT LLKL ATPA RFSQ TVSA VCLP SADD DFPA GTLC ATTG WGKT KYNA NKTP DKLQ QAAL PLLS NAEC KKSW GRRI TDVM ICAG ASGV SSCM GDSG GPLV CQKD GAWT LVGI VSWG SDTC STSS PGVY ARVT KLIP WVQK ILAA N |
| 遺伝子ID: | 1504 |
| Uniprot: | P17538 |
| セルラーロケーション: | Secreted, extracellular space |
| 計算された分子量: | 27kDa |
| 観察された分子量: | 28kDa |
| 同義語: | CTRB1, CTRB |
| バックグラウンド: | This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. |
| UniProt Protein Function: | CTRB1: is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011] |
| UniProt Protein Details: | Protein type:EC 3.4.21.1; Secreted, signal peptide; Protease; Secreted; Apoptosis Chromosomal Location of Human Ortholog: 16q23.1 Cellular Component: extracellular region; extracellular space Molecular Function:serine-type endopeptidase activity Biological Process: cobalamin metabolic process; digestion; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis; vitamin metabolic process; water-soluble vitamin metabolic process |
| NCBI Summary: | The protein encoded by this gene is one of a family of serine proteases that is secreted into the gastrointestinal tract as an inactive precursor, which is activated by proteolytic cleavage with trypsin. [provided by RefSeq, Oct 2011] |
| UniProt Code: | P17538 |
| NCBI GenInfo Identifier: | 117617 |
| NCBI Gene ID: | 1504 |
| NCBI Accession: | P17538.1 |
| UniProt Related Accession: | P17538 |
| Molecular Weight: | 27,870 Da |
| NCBI Full Name: | Chymotrypsinogen B |
| NCBI Synonym Full Names: | chymotrypsinogen B1 |
| NCBI Official Symbol: | CTRB1 |
| NCBI Official Synonym Symbols: | CTRB |
| NCBI Protein Information: | chymotrypsinogen B |
| UniProt Protein Name: | Chymotrypsinogen B |
| Protein Family: | Chymotrypsinogen |
| UniProt Gene Name: | CTRB1 |
| UniProt Entry Name: | CTRB1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CTRB1 antibody (CAB15043) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunohistochemistry of paraffin-embedded mouse lung using CTRB1 antibody (CAB15043) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse pancreas using CTRB1 antibody (CAB15043) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of rat pancreas using CTRB1 Polyclonal Antibody (CAB15043) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse pancreas using CTRB1 Polyclonal Antibody (CAB15043) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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