Anti-CST8 Antibody (CAB1224)
- SKU:
- CAB1224
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CST8 Antibody |
| 抗体コード: | CAB1224 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 53-142 of human CST8 (NP_005483.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse testis, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 53-142 of human CST8 (NP_005483.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MQEY NKES EDKY VFLV VKTL QAQL QVTN LLEY LIDV EIAR SDCR KPLS TNEI CAIQ ENSK LKRK LSCS FLVG ALPW NGEF TVME KKCE DA |
| 遺伝子ID: | 10047 |
| Uniprot: | O60676 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 16kDa |
| 観察された分子量: | 27kDa |
| 同義語: | CST8, CRES, CTES5 |
| バックグラウンド: | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | CST8: Performs a specialized role during sperm development and maturation. Belongs to the cystatin family. |
| UniProt Protein Details: | Protein type:Inhibitor; Secreted; Cell surface; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20p11.21 Cellular Component: cell surface; cytoplasm; extracellular region Molecular Function:cysteine protease inhibitor activity |
| NCBI Summary: | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| UniProt Code: | O60676 |
| NCBI GenInfo Identifier: | 6225205 |
| NCBI Gene ID: | 10047 |
| NCBI Accession: | O60676.1 |
| UniProt Secondary Accession: | O60676,Q2M2X6, |
| UniProt Related Accession: | O60676 |
| Molecular Weight: | 142 |
| NCBI Full Name: | Cystatin-8 |
| NCBI Synonym Full Names: | cystatin 8 (cystatin-related epididymal specific) |
| NCBI Official Symbol: | CST8 |
| NCBI Official Synonym Symbols: | CRES; CTES5 |
| NCBI Protein Information: | cystatin-8; cystatin-related epididymal spermatogenic protein |
| UniProt Protein Name: | Cystatin-8 |
| UniProt Synonym Protein Names: | Cystatin-related epididymal spermatogenic protein |
| Protein Family: | Cystatin |
| UniProt Gene Name: | CST8 |
| UniProt Entry Name: | CST8_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CST8 antibody (CAB1224) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunofluorescence analysis of HeLa cells using CST8 antibody (CAB1224). Blue: DAPI for nuclear staining. |
View AllClose