Anti-CSRP2BP Antibody (CAB7380)
- SKU:
- CAB7380
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CSRP2BP Antibody |
| 抗体コード: | CAB7380 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 523-782 of human CSRP2BP (NP_065397.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HL-60, A375, SW480, Mouse kidney, Mouse heart, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 523-782 of human CSRP2BP (NP_065397.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DGIY GAKE GGIS RLPA GQAT YRTT CQDF RILD RYQT SLPS RKGF RHQT TKFL YRLV GSED MAVD QSIV SPYT SRIL KPYI RRDY ETKP PKLQ LLSQ IRSH LHRS DPHW TPEP DAPL DYCY VRPN HIPT INSM CQEF FWPG IDLS ECLQ YPDF SVVV LYKK VIIA FGFM VPDV KYNE AYIS FLFV HPEW RRAG IATF MIYH LIQT CMGK DVTL HVSA SNPA MLLY QKFG FKTE EYVL DFYD KYYP LEST ECKH AFFL RLRR |
| 遺伝子ID: | 57325 |
| Uniprot: | Q9H8E8 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 74kDa/88kDa |
| 観察された分子量: | 89kDa |
| 同義語: | KAT14, ATAC2, CRP2BP, CSRP2BP, PRO1194, dJ717M23.1 |
| バックグラウンド: | CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | CSRP2BP: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. May function as a scaffold for the ATAC complex to promote ATAC complex stability. Has also weak histone acetyltransferase activity toward histone H4. Required for the normal progression through G1 and G2/M phases of the cell cycle. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 20p11.23 Cellular Component: cytoplasm; nucleus Molecular Function:histone acetyltransferase activity; LIM domain binding; protein binding Biological Process: establishment and/or maintenance of chromatin architecture; G2/M transition of mitotic cell cycle |
| NCBI Summary: | CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011] |
| UniProt Code: | Q9H8E8 |
| NCBI GenInfo Identifier: | 308153608 |
| NCBI Gene ID: | 57325 |
| NCBI Accession: | Q9H8E8.3 |
| UniProt Related Accession: | Q9H8E8 |
| Molecular Weight: | 89 kDa |
| NCBI Full Name: | Cysteine-rich protein 2-binding protein |
| NCBI Synonym Full Names: | lysine acetyltransferase 14 |
| NCBI Official Symbol: | KAT14 |
| NCBI Official Synonym Symbols: | ATAC2; CRP2BP; CSRP2BP; PRO1194; dJ717M23.1 |
| NCBI Protein Information: | cysteine-rich protein 2-binding protein |
| UniProt Protein Name: | Cysteine-rich protein 2-binding protein |
| UniProt Synonym Protein Names: | ADA2A-containing complex subunit 2; ATAC2; CRP2-binding partner; CRP2BP |
| Protein Family: | Cysteine-rich protein 2-binding protein |
| UniProt Gene Name: | CSRP2BP |
| UniProt Entry Name: | CSR2B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSRP2BP antibody (CAB7380) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human kidney using CSRP2BP antibody (CAB7380) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of A549 cells using CSRP2BP antibody (CAB7380). Blue: DAPI for nuclear staining. |
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