Anti-CSRP1 Antibody (CAB19842)[KO Validated]

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SKU:
CAB19842
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-CSRP1 Antibody [KO Validated]
抗体コード:CAB19842
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IP RIP
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant protein of human CSRP1.
申し込み:WB IP RIP
推奨希釈:WB 1:500 - 1:2000 IP 1:50 - 1:200 RIP 1:20 - 1:50
反応性:Human, Mouse
ポジティブサンプル:HeLa
免疫原:Recombinant protein of human CSRP1.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:1465
Uniprot:P21291
セルラーロケーション:Nucleus
計算された分子量:20kDa
観察された分子量:19KDa
Anti-CSRP1 Antibody [KO Validated] (CAB19842)Western blot analysis of extracts from normal (control) and CSRP1 knockout (KO) HeLa cells, using CSRP1 antibody (CAB19842) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
同義語:CSRP1, CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286
バックグラウンド:This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described.
UniProt Protein Function:CSRP1: a LIM protein. Involved in the noncanonical Wnt pathway, which coordinates cell behaviors during dynamic morphogenetic movements of tissues and organs. Interacts with Dishevelled 2 (Dvl2) and Diversin (Div) in zebrafish. Displays coordinate serum induction with c-myc.
UniProt Protein Details:

Protein type:Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: focal adhesion; nucleus

Molecular Function:zinc ion binding

NCBI Summary:This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
UniProt Code:P21291
NCBI GenInfo Identifier:118161
NCBI Gene ID:1465
NCBI Accession:P21291.3
UniProt Secondary Accession:P21291,Q5U0J2, A8K268,
UniProt Related Accession:P21291
Molecular Weight:193
NCBI Full Name:Cysteine and glycine-rich protein 1
NCBI Synonym Full Names:cysteine and glycine-rich protein 1
NCBI Official Symbol:CSRP1  
NCBI Official Synonym Symbols:CRP; CRP1; CSRP; CYRP; D1S181E; HEL-141  
NCBI Protein Information:cysteine and glycine-rich protein 1; LIM-domain protein; cysteine-rich protein 1; epididymis luminal protein 141
UniProt Protein Name:Cysteine and glycine-rich protein 1
UniProt Synonym Protein Names:Cysteine-rich protein 1; CRP; CRP1; Epididymis luminal protein 141; HEL-141
Protein Family:Cysteine and glycine-rich protein
UniProt Gene Name:CSRP1  
UniProt Entry Name:CSRP1_HUMAN
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