Anti-CSF3R Antibody (CAB16823)
- SKU:
- CAB16823
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CSF3R Antibody |
| 抗体コード: | CAB16823 |
| 抗体サイズ: | 20uL, 50 uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CSF3R (NP_000751.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CSF3R (NP_000751.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CSPN RKNP LWPS VPDP AHSS LGSW VPTI MEED AFQL PGLG TPPI TKLT VLEE DEKK PVPW ESHN SSET CGLP TLVQ TYVL QGDP RAVS TQPQ SQSG TSDQ V |
| 遺伝子ID: | 1441 |
| Uniprot: | Q99062 |
| セルラーロケーション: | |
| 計算された分子量: | 85kDa/86kDa/92kDa/95kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | CSF3R, CD114, GCSFR, SCN7 |
| バックグラウンド: | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
| UniProt Protein Function: | GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Receptor, cytokine; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p35-p34.3 Cellular Component: integral to plasma membrane; extracellular region Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity Biological Process: neutrophil chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; cell adhesion; signal transduction Disease: Neutrophilia, Hereditary |
| NCBI Summary: | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q99062 |
| NCBI GenInfo Identifier: | 729564 |
| NCBI Gene ID: | 1441 |
| NCBI Accession: | Q99062.1 |
| UniProt Related Accession: | Q99062 |
| Molecular Weight: | |
| NCBI Full Name: | Granulocyte colony-stimulating factor receptor |
| NCBI Synonym Full Names: | colony stimulating factor 3 receptor (granulocyte) |
| NCBI Official Symbol: | CSF3R |
| NCBI Official Synonym Symbols: | CD114; GCSFR |
| NCBI Protein Information: | granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor |
| UniProt Protein Name: | Granulocyte colony-stimulating factor receptor |
| UniProt Synonym Protein Names: | CD_antigen: CD114 |
| Protein Family: | Granulocyte colony-stimulating factor receptor |
| UniProt Gene Name: | CSF3R |
| UniProt Entry Name: | CSF3R_HUMAN |