Anti-CSF3R Antibody (CAB13964)
- SKU:
- CAB13964
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CSF3R Antibody |
| 抗体コード: | CAB13964 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IHC |
| 反応性: | Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human CSF3R (NP_000751.1). |
| 申し込み: | IHC |
| 推奨希釈: | IHC 1:50 - 1:200 |
| 反応性: | Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-290 of human CSF3R (NP_000751.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SVSA PIVH LGDP ITAS CIIK QNCS HLDP EPQI LWRL GAEL QPGG RQQR LSDG TQES IITL PHLN HTQA FLSC CLNW GNSL QILD QVEL RAGY PPAI PHNL SCLM NLTT SSLI CQWE PGPE THLP TSFT LKSF KSRG NCQT QGDS ILDC VPKD GQSH CCIP RKHL LLYQ NMGI WVQA ENAL GTSM SPQL CLDP MDVV KLEP PMLR TMDP SPEA APPQ AGCL QLCW EPWQ PGLH INQK CELR HKPQ RGEA SWAL VGPL PLEA L |
| 遺伝子ID: | 1441 |
| Uniprot: | Q99062 |
| セルラーロケーション: | Cell membrane, Secreted, Single-pass type I membrane protein |
| 計算された分子量: | 85kDa/86kDa/92kDa/95kDa |
| 観察された分子量: |
| 同義語: | CSF3R, CD114, GCSFR, SCN7 |
| バックグラウンド: | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
| UniProt Protein Function: | GCSFR: the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Receptor, cytokine; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p35-p34.3 Cellular Component: integral to plasma membrane; extracellular region Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity Biological Process: neutrophil chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; cell adhesion; signal transduction Disease: Neutrophilia, Hereditary |
| NCBI Summary: | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010] |
| UniProt Code: | Q99062 |
| NCBI GenInfo Identifier: | 729564 |
| NCBI Gene ID: | 1441 |
| NCBI Accession: | Q99062.1 |
| UniProt Related Accession: | Q99062 |
| Molecular Weight: | |
| NCBI Full Name: | Granulocyte colony-stimulating factor receptor |
| NCBI Synonym Full Names: | colony stimulating factor 3 receptor (granulocyte) |
| NCBI Official Symbol: | CSF3R |
| NCBI Official Synonym Symbols: | CD114; GCSFR |
| NCBI Protein Information: | granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor |
| UniProt Protein Name: | Granulocyte colony-stimulating factor receptor |
| UniProt Synonym Protein Names: | CD_antigen: CD114 |
| Protein Family: | Granulocyte colony-stimulating factor receptor |
| UniProt Gene Name: | CSF3R |
| UniProt Entry Name: | CSF3R_HUMAN |
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