Anti-CSF2RB Antibody (CAB10501)
- SKU:
- CAB10501
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CSF2RB Antibody |
| 抗体コード: | CAB10501 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-443 of human CSF2RB (NP_000386.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, Mouse spleen, Mouse liver, Mouse lung, Mouse thymus, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-443 of human CSF2RB (NP_000386.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | EHLM PSST YVAR VRTR LAPG SRLS GRPS KWSP EVCW DSQP GDEA QPQN LECF FDGA AVLS CSWE VRKE VASS VSFG LFYK PSPD AGEE ECSP VLRE GLGS LHTR HHCQ IPVP DPAT HGQY IVSV QPRR AEKH IKSS VNIQ MAPP SLNV TKDG DSYS LRWE TMKM RYEH IDHT FEIQ YRKD TATW KDSK TETL QNAH SMAL PALE PSTR YWAR VRVR TSRT GYNG IWSE WSEA RSWD TESV LPMW |
| 遺伝子ID: | 1439 |
| Uniprot: | P32927 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 97kDa |
| 観察された分子量: | 130kDa |
| 同義語: | CSF2RB, CD131, CDw131, IL3RB, IL5RB, SMDP5 |
| バックグラウンド: | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). |
| UniProt Protein Function: | CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane Molecular Function:interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5 |
| NCBI Summary: | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008] |
| UniProt Code: | P32927 |
| NCBI GenInfo Identifier: | 1345923 |
| NCBI Gene ID: | 1439 |
| NCBI Accession: | P32927.2 |
| UniProt Secondary Accession: | P32927,Q5JZI1, Q6ICE0, |
| UniProt Related Accession: | P32927 |
| Molecular Weight: | 97,976 Da |
| NCBI Full Name: | Cytokine receptor common subunit beta |
| NCBI Synonym Full Names: | colony stimulating factor 2 receptor beta common subunit |
| NCBI Official Symbol: | CSF2RB |
| NCBI Official Synonym Symbols: | CD131; IL3RB; IL5RB; SMDP5; CDw131 |
| NCBI Protein Information: | cytokine receptor common subunit beta |
| UniProt Protein Name: | Cytokine receptor common subunit beta |
| UniProt Synonym Protein Names: | CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131 |
| Protein Family: | Cytokine receptor |
| UniProt Gene Name: | CSF2RB |
| UniProt Entry Name: | IL3RB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CSF2RB antibody (CAB10501) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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