Anti-CPSF1 Antibody (CAB17144)
- SKU:
- CAB17144
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-CPSF1 Antibody |
| 抗体コード: | CAB17144 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_037423.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | 293T, NIH/3T3, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human CPSF1 (NP_037423.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LYRD LSGM FTTE SRLG GARD ELGG RSGP EAEG LGSE TSPT VDDE EEML YGDS GSLF SPSK EEAR RSSQ PPAD RDPA PFRA EPTH WCLL VREN GTME IYQL PDWR LVFL VKNF PVGQ RVLV DSSF GQPT TQGE ARRE EATR QGEL PLVK EVLL VALG SRQS RPYL LVHV DQEL LIYE AFPH DSQL GQGN LKVR FKKV PHNI NFRE KKPK PSKK KAEG GGAE EGAG ARGR VARF RYFE DIYG YSGV FICG PSP |
| 遺伝子ID: | 29894 |
| Uniprot: | Q10570 |
| セルラーロケーション: | |
| 計算された分子量: | 160kDa |
| 観察された分子量: | 170kDa/185kDa |
 | Western blot - CPSF1 Polyclonal Antibody (CAB17144) |
| 同義語: | CPSF1, CPSF160, HSU37012, P/cl.18 |
| バックグラウンド: | Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]). |
| UniProt Protein Function: | Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. |
| NCBI Summary: | Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q10570 |
| NCBI GenInfo Identifier: | 56676371 |
| NCBI Gene ID: | 29894 |
| NCBI Accession: | NP_037423.2 |
| UniProt Secondary Accession: | Q10570,Q96AF0, |
| UniProt Related Accession: | Q10570 |
| Molecular Weight: | 160,884 Da |
| NCBI Full Name: | cleavage and polyadenylation specificity factor subunit 1 |
| NCBI Synonym Full Names: | cleavage and polyadenylation specific factor 1 |
| NCBI Official Symbol: | CPSF1 |
| NCBI Official Synonym Symbols: | CPSF160; P/cl.18; HSU37012 |
| NCBI Protein Information: | cleavage and polyadenylation specificity factor subunit 1 |
| UniProt Protein Name: | Cleavage and polyadenylation specificity factor subunit 1 |
| UniProt Synonym Protein Names: | Cleavage and polyadenylation specificity factor 160 kDa subunit; CPSF 160 kDa subunit |
| UniProt Gene Name: | CPSF1 |