Anti-CPA3 Antibody (CAB15658)
- SKU:
- CAB15658
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CPA3 Antibody |
| 抗体コード: | CAB15658 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-417 of human CPA3 (NP_001861.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse pancreas, Rat pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-417 of human CPA3 (NP_001861.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IPGR HSYA KYNN WEKI VAWT EKMM DKYP EMVS RIKI GSTV EDNP LYVL KIGE KNER RKAI FTDC GIHA REWV SPAF CQWF VYQA TKTY GRNK IMTK LLDR MNFY ILPV FNVD GYIW SWTK NRMW RKNR SKNQ NSKC IGTD LNRN FNAS WNSI PNTN DPCA DNYR GSAP ESEK ETKA VTNF IRSH LNEI KVYI TFHS YSQM LLFP YGYT SKLP PNHE DLAK VAKI GTDV LSTR YETR YIYG PIES TIYP ISGS SLDW AYDL GIKH TFAF ELRD KGKF GFLL PESR IKPT CRET MLAV KFIA KYIL KHTS |
| 遺伝子ID: | 1359 |
| Uniprot: | P15088 |
| セルラーロケーション: | Cytoplasmic vesicle, secretory vesicle |
| 計算された分子量: | 48kDa |
| 観察された分子量: | 55kDa |
| 同義語: | CPA3, MC-CPA |
| バックグラウンド: | This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. The encoded preproprotein is proteolytically processed to generate a mature protease that is released by mast cells and may be involved in the degradation of endogenous proteins and the inactivation of venom-associated peptides. Expression of this gene may be elevated in human asthma patients. |
| UniProt Protein Function: | CPA3: Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a form which is obtained as a binary complex of a procarboxypeptidase A with proproteinase E and functions as a secretory granule metalloexopeptidase. [provided by RefSeq, Jan 2009] |
| UniProt Protein Details: | Protein type:EC 3.4.17.1; Protease Chromosomal Location of Human Ortholog: 3q24 Cellular Component: extracellular region; extracellular space Molecular Function:metallocarboxypeptidase activity Biological Process: angiotensin maturation; positive regulation of defense response to virus by host; proteolysis |
| NCBI Summary: | This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. The encoded preproprotein is proteolytically processed to generate a mature protease that is released by mast cells and may be involved in the degradation of endogenous proteins and the inactivation of venom-associated peptides. Expression of this gene may be elevated in human asthma patients. [provided by RefSeq, Nov 2015] |
| UniProt Code: | P15088 |
| NCBI GenInfo Identifier: | 317373331 |
| NCBI Gene ID: | 1359 |
| NCBI Accession: | P15088.2 |
| UniProt Secondary Accession: | P15088,Q96E94, |
| UniProt Related Accession: | P15088 |
| Molecular Weight: | 48,670 Da |
| NCBI Full Name: | Mast cell carboxypeptidase A |
| NCBI Synonym Full Names: | carboxypeptidase A3 |
| NCBI Official Symbol: | CPA3 |
| NCBI Official Synonym Symbols: | MC-CPA |
| NCBI Protein Information: | mast cell carboxypeptidase A |
| UniProt Protein Name: | Mast cell carboxypeptidase A |
| UniProt Synonym Protein Names: | Carboxypeptidase A3 |
| Protein Family: | Mast cell carboxypeptidase |
| UniProt Gene Name: | CPA3 |
| UniProt Entry Name: | CBPA3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CPA3 antibody (CAB15658) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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