Anti-COX8A Antibody (CAB3290)
- SKU:
- CAB3290
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-COX8A Antibody |
抗体コード: | CAB3290 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human COX8A (NP_004065.1). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse skeletal muscle |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human COX8A (NP_004065.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSVL TPLL LRGL TGSA RRLP VPRA KIHS LPPE GKLG IMEL AVGL TSCF VTFL LPAG WILS HLET YRRP E |
遺伝子ID: | 1351 |
Uniprot: | P10176 |
セルラーロケーション: | Mitochondrion inner membrane |
計算された分子量: | 7kDa |
観察された分子量: | 8kDa |
同義語: | COX8A, COX, COX8, COX8-2, COX8L, VIII, VIII-L |
バックグラウンド: | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. |
UniProt Protein Function: | COX8A: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIII family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 11q12-q13 Cellular Component: mitochondrial inner membrane; integral to membrane Molecular Function:cytochrome-c oxidase activity Biological Process: cellular metabolic process; generation of precursor metabolites and energy; transmembrane transport |
NCBI Summary: | The protein encoded by this gene is the terminal enzyme of the respiratory chain, coupling the transfer of electrons from cytochrome c to molecular oxygen, with the concomitant production of a proton electrochemical gradient across the inner mitochondrial membrane. In addition to 3 mitochondrially encoded subunits, which perform the catalytic function, the eukaryotic enzyme contains nuclear-encoded smaller subunits, ranging in number from 4 in some organisms to 10 in mammals. It has been proposed that nuclear-encoded subunits may be involved in the modulation of the catalytic function. This gene encodes one of the nuclear-encoded subunits. [provided by RefSeq, Jul 2008] |
UniProt Code: | P10176 |
NCBI GenInfo Identifier: | 117132 |
NCBI Gene ID: | 1351 |
NCBI Accession: | P10176.2 |
UniProt Secondary Accession: | P10176,P15955, |
UniProt Related Accession: | P10176 |
Molecular Weight: | 7,579 Da |
NCBI Full Name: | Cytochrome c oxidase subunit 8A, mitochondrial |
NCBI Synonym Full Names: | cytochrome c oxidase subunit VIIIA (ubiquitous) |
NCBI Official Symbol: | COX8A |
NCBI Official Synonym Symbols: | COX; COX8; VIII; COX8L; COX8-2; VIII-L |
NCBI Protein Information: | cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase polypeptide VIII-liver/heart; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit 8A (ubiquitous); cytochrome c oxidase subunit VIII |
UniProt Protein Name: | Cytochrome c oxidase subunit 8A, mitochondrial |
UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide VIII-liver/heart; Cytochrome c oxidase subunit 8-2 |
UniProt Gene Name: | COX8A |
UniProt Entry Name: | COX8A_HUMAN |
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