Anti-COX6C Antibody (CAB16250)
- SKU:
- CAB16250
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-COX6C Antibody |
| 抗体コード: | CAB16250 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-75 of human COX6C (NP_004365.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Mouse |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-75 of human COX6C (NP_004365.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAPE VLPK PRMR GLLA RRLR NHMA VAFV LSLG VAAL YKFR VADQ RKKA YADF YRNY DVMK DFEE MRKA GIFQ SVK |
| 遺伝子ID: | 1345 |
| Uniprot: | P09669 |
| セルラーロケーション: | |
| 計算された分子量: | 8kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | COX6C |
| バックグラウンド: | Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. |
| UniProt Protein Function: | COX6C: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 6c family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Mitochondrial; EC 1.9.3.1 Chromosomal Location of Human Ortholog: 8q22.2 Cellular Component: mitochondrial inner membrane; mitochondrion Biological Process: generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen |
| NCBI Summary: | Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010] |
| UniProt Code: | P09669 |
| NCBI GenInfo Identifier: | 1352175 |
| NCBI Gene ID: | 1345 |
| NCBI Accession: | P09669.2 |
| UniProt Secondary Accession: | P09669,B2R4D7, |
| UniProt Related Accession: | P09669 |
| Molecular Weight: | 8,781 Da |
| NCBI Full Name: | Cytochrome c oxidase subunit 6C |
| NCBI Synonym Full Names: | cytochrome c oxidase subunit 6C |
| NCBI Official Symbol: | COX6C |
| NCBI Protein Information: | cytochrome c oxidase subunit 6C |
| UniProt Protein Name: | Cytochrome c oxidase subunit 6C |
| UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide VIc |
| Protein Family: | Cytochrome c oxidase |
| UniProt Gene Name: | COX6C |
| UniProt Entry Name: | COX6C_HUMAN |
 | Immunofluorescence analysis of NIH/3T3 cells using COX6C antibody (CAB16250) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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