Anti-CORO2A Antibody (CAB14469)
- SKU:
- CAB14469
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-CORO2A Antibody |
| 抗体コード: | CAB14469 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human CORO2A (NP_003380.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HT-29, OVCAR3, Mouse eye, Rat eye |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human CORO2A (NP_003380.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | QPSL TAQE WLSG MNRD PILV SLRP GSEL LRPH PLPA ERPI FNSM APAS PRLL NQTE KLAA EDGW RSSS LLEE KMPR WAAE HRLE EKKT WLTN GFDV FECP PPKT ENEL LQMF YRQQ EEIR RLRE LLTQ REVQ AKQL ELEI KNLR MGSE QL |
| 遺伝子ID: | 7464 |
| Uniprot: | Q92828 |
| セルラーロケーション: | |
| 計算された分子量: | 59kDa |
| 観察された分子量: | 60kDa |
| 同義語: | CORO2A, CLIPINB, IR10, WDR2 |
| バックグラウンド: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. |
| UniProt Protein Function: | coronin 2A: a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 9q22.3 Cellular Component: actin cytoskeleton; transcriptional repressor complex Molecular Function:actin filament binding Biological Process: actin cytoskeleton organization and biogenesis |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92828 |
| NCBI GenInfo Identifier: | 28381354 |
| NCBI Gene ID: | 7464 |
| NCBI Accession: | Q92828.2 |
| UniProt Secondary Accession: | Q92828,Q5TBR5, Q92829, Q9BWS5, |
| UniProt Related Accession: | Q92828 |
| Molecular Weight: | 59,763 Da |
| NCBI Full Name: | Coronin-2A |
| NCBI Synonym Full Names: | coronin 2A |
| NCBI Official Symbol: | CORO2A |
| NCBI Official Synonym Symbols: | IR10; WDR2; CLIPINB |
| NCBI Protein Information: | coronin-2A |
| UniProt Protein Name: | Coronin-2A |
| UniProt Synonym Protein Names: | IR10; WD repeat-containing protein 2 |
| Protein Family: | Coronin |
| UniProt Gene Name: | CORO2A |
| UniProt Entry Name: | COR2A_HUMAN |
 | Western blot analysis of extracts of various cell lines, using CORO2A antibody (CAB14469) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
View AllClose