Anti-COPG1 Antibody (CAB10551)
- SKU:
- CAB10551
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-COPG1 Antibody |
抗体コード: | CAB10551 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 555-874 of human COPG1 (NP_057212.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, A375, BT-474, Mouse liver, Mouse kidney, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 555-874 of human COPG1 (NP_057212.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | IPGL ERAL QQYT LEPS EKPF DLKS VPLA TAPM AEQR TEST PITA VKQP EKVA ATRQ EIFQ EQLA AVPE FRGL GPLF KSSP EPVA LTES ETEY VIRC TKHT FTNH MVFQ FDCT NTLN DQTL ENVT VQME PTEA YEVL CYVP ARSL PYNQ PGTC YTLV ALPK EDPT AVAC TFSC MMKF TVKD CDPT TGET DDEG YEDE YVLE DLEV TVAD HIQK VMKL NFEA AWDE VGDE FEKE ETFT LSTI KTLE EAVG NIVK FLGM HPCE RSDK VPDN KNTH TLLL AGVF RGGH DILV RSRL LLLD TVTM QVTA RSLE ELPV DIIL ASVG |
遺伝子ID: | 22820 |
Uniprot: | Q9Y678 |
セルラーロケーション: | COPI-coated vesicle membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus membrane, Peripheral membrane protein |
計算された分子量: | 97kDa |
観察された分子量: | 105kDa |
同義語: | COPG1, COPG |
バックグラウンド: |
UniProt Protein Function: | COPG: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis. Belongs to the COPG family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: Golgi membrane; COPI vesicle coat; cytosol Molecular Function:protein binding; structural molecule activity Biological Process: intracellular protein transport; COPI coating of Golgi vesicle; establishment of Golgi localization; retrograde vesicle-mediated transport, Golgi to ER |
UniProt Code: | Q9Y678 |
NCBI GenInfo Identifier: | 12229771 |
NCBI Gene ID: | 22820 |
NCBI Accession: | Q9Y678.1 |
UniProt Secondary Accession: | Q9Y678,Q54AC4, A8K6M8, B3KMF6, |
UniProt Related Accession: | Q9Y678 |
Molecular Weight: | 874 |
NCBI Full Name: | Coatomer subunit gamma-1 |
NCBI Synonym Full Names: | coatomer protein complex, subunit gamma 1 |
NCBI Official Symbol: | COPG1 |
NCBI Official Synonym Symbols: | COPG |
NCBI Protein Information: | coatomer subunit gamma-1; gamma-COP; gamma-1-COP; gamma-coat protein; gamma-1-coat protein; coat protein gamma-cop |
UniProt Protein Name: | Coatomer subunit gamma-1 |
UniProt Synonym Protein Names: | Gamma-1-coat protein; Gamma-1-COP |
Protein Family: | Coatomer |
UniProt Gene Name: | COPG1 |
UniProt Entry Name: | COPG1_HUMAN |
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